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Comparative Analysis of Emerging B.1.1.7+E484K SARS-CoV-2 Isolates.
Moustafa, Ahmed M; Bianco, Colleen; Denu, Lidiya; Ahmed, Azad; Coffin, Susan E; Neide, Brandy; Everett, John; Reddy, Shantan; Rabut, Emilie; Deseignora, Jasmine; Feldman, Michael D; Rodino, Kyle G; Bushman, Frederic; Harris, Rebecca M; Chang Mell, Josh; Planet, Paul J.
Open Forum Infect Dis ; 8(7): ofab300, 2021 Jul.
Article in English | MEDLINE | ID: mdl-34254040

ABSTRACT

We report the genome of a B.1.1.7+E484K severe acute respiratory syndrome coronavirus 2 from Southeastern Pennsylvania and compare it with all high-coverage B.1.1.7+E484K genomes (n = 235) available. Analyses showed the existence of at least 4 distinct clades of this variant circulating in the United States and the possibility of at least 59 independent acquisitions of the E484K mutation.

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