ABSTRACT
A case of neurofibromatosis involving the larynx is added to the 19 previously reported cases; furthermore, it represents the only reported case of plexiform ganglioneurofibroma of the larynx in Von Recklinghausen's disease. The reported cases of neurofibromatosis with laryngeal involvement in the world literature are discussed and summarized. The main clinical symptoms are dyspnea, dysphonia and dysphagia which occasionally require tracheotomy when the condition is recognized. Elective surgical excision is the treatment of choice.
Subject(s)
Laryngeal Neoplasms/pathology , Neurofibromatosis 1/pathology , Child, Preschool , Humans , Laryngeal Neoplasms/diagnosis , Male , Neurofibromatosis 1/diagnosisABSTRACT
The purpose of the study was to examine the relationship between the histologic findings and the presence or absence of ABH isoantigens in intraepithelial neoplasia of the cervix. After the lesions were graded by four pathologists, the Red Cell Adherence (RCA) test was done to demonstrate the ABH antigens, and the results of the two were compared. The correlation between the morphologic diagnosis and the results of the RCA test was limited. The percentages of tissues giving positive (+) or positive-negative (+/-) reactions were very similar in intraepithelial neoplsia (59.2%) and normal squamous epithelium (58.4%). The relationship of the RCA test results and behavior of the lesion was not studied.
Subject(s)
ABO Blood-Group System/analysis , Uterine Cervical Neoplasms/blood , Carcinoma/pathology , Carcinoma in Situ/blood , Epithelium/pathology , Female , Humans , Immune Adherence Reaction , Prognosis , Uterine Cervical Neoplasms/pathologyABSTRACT
A case report of Gaucher's disease associated with chronic lymphocytic leukaemia is described in a patient with gout and carcinoma of the sigmoid colon. This the first reported case of Gaucher's disease associated with chronic lymphocytic leukaemia.
