ABSTRACT
PURPOSE: To explore the efficacy of a radioisotopic (RI) method in detecting sentinel lymph nodes (SLNs), known as sites of harboring metastases, in localized high-risk prostate cancer (HRPC). METHODS: The RI method was applied to 26 males with clinically localized HRPC, subjected to radical prostatectomy in 2006-2008. All had poor pathological characteristics: initial PSA > 15 ng/ml, Gleason score > 7, clinically suspected extracapsular extension, seminal vesicle invasion, and/or positive pelvic lymph nodes (LNs). The radiopharmaceutical (Tc-99m) was injected preoperatively at 4 zones of the periphery of the prostate. Tc-99m-nanocolloid particles were Subject(s)
Lymph Nodes/diagnostic imaging
, Prostatic Neoplasms/diagnostic imaging
, Radiopharmaceuticals
, Sentinel Lymph Node Biopsy
, Technetium Tc 99m Aggregated Albumin
, Aged
, Humans
, Lymph Node Excision
, Lymph Nodes/pathology
, Lymph Nodes/surgery
, Lymphatic Metastasis
, Male
, Middle Aged
, Neoplasm Staging
, Prognosis
, Prostatic Neoplasms/pathology
, Prostatic Neoplasms/surgery
, Radionuclide Imaging
, Retrospective Studies
