[The effect of an agluten diet on cellular immunity in adult patients with celiac disease]. / Vliianie agliutenovoi diety na pokazateli kletochnogo immuniteta u bol'nykh tseliakiei vzroslykh.

A total of 45 patients with Gee's disease of adults were followed up in the time course of 6 months to 3 years. In untreated patients the number of T-lymphocytes was decreased both at the expense of T-helpers and, especially, of T-suppressors. Lymphokine-producing activity of T-lymphocytes, according to the production degree of the mediator, inhibiting monocyte adherence, increases after gliadin-treatment of the immuno-competent cells, that leads to monocyte adhesion decrease. In patients strictly keeping the agluten diet the cellular immunity parameters return to normal. Decreased monocyte adhesion remains up to a year. In those who do not strictly keep the agluten diet the cellular immunity disorders are retained and become more pronounced than in the untreated patients.

[Effect of diet therapy on the state of the intestinal barrier in digestive organ diseases]. / Vliianie dietoterapii na sostoianie kishechnogo bar'era u bol'nykh s nekotorymi zabolevaniiami organov pishchevareniia.

The effect of diets with varying amount of protein (135 and 160 g) on the intestinal barrier was studied in patients with the inadequate absorption syndrome of different etiology (chronic enterocolitis, the postgastroresection syndrome, chronic colitis). The data obtained indicate that in spite of the progress attained in the care of such patients at the present time, they show disturbed permeability of the intestinal barrier, determined by the passive hemagglutination test (PHAT) with diverse fractions of milk protein. With the postgastroresection syndrome, the abnormalities in the intestinal barrier arise less frequently, are less pronounced and more amenable by therapy as compared to patients with chronic enterocolitis. However, the condition of the small intestine should be taken into consideration in making dietetic recommendations for the patients suffering from the above diseases. The clinical findings and PHAT dynamics indicate that inclusion into the diet of over 135 g protein is not desirable.