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Pak J Biol Sci ; 16(21): 1318-23, 2013 Nov 01.
Article in English | MEDLINE | ID: mdl-24511740

ABSTRACT

Phytochemicals are extensively found at different levels in many medicinal plants. To investigate the phenolic compound content and in vitro antioxidant activity of hydro-methanolic extract from Prasium majus L. (Lamiaceae). The present investigation comprises, estimation of total polyphenol, flavonoid, tannin, in vitro antioxidant assays such as total antioxidant capacity, DPPH, ABTS, beta-carotene and ferric reducing power. P. majus exhibited 64.25 mg GAE g(-1) extract of polyphenol phenol content and better scavenging activity of DPPH (IC50 = 7.95 microg mL(-1)), ABTS*+ (IC50 = 373.78 microg mL(-1)) and beta-carotene (IC50 = 122.56 microg mL(-1)). Our results clearly demonstrated that hydro-methanolic extract P. majus has antioxidant capacity. Therefore is a valuable source of natural antioxidants.


Subject(s)
Antioxidants/chemistry , Antioxidants/pharmacology , Lamiaceae/chemistry , Plant Extracts/chemistry , Plant Extracts/pharmacology , Benzothiazoles/chemistry , Biphenyl Compounds/chemistry , Flavonoids/chemistry , Flavonoids/pharmacology , Methanol/chemistry , Phenols/chemistry , Picrates/chemistry , Plants, Medicinal/chemistry , Polyphenols/chemistry , Polyphenols/pharmacology , Sulfonic Acids/chemistry , Tannins/chemistry , Tannins/pharmacology , beta Carotene/chemistry
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