ABSTRACT
OBJECTIVE: To examine the pattern of stroke subtypes found on Computed Tomography (CT), Magnetic Resonance Imaging (MRI) at the University Hospital of the West Indies (UHWI), Kingston, Jamaica. METHOD: A retrospective review was conducted for all patients diagnosed with stroke and who were subjected to CT or MRI evaluation at UHWI between January 2001 and December 2004. Data were collected for patient age and gender and type of stroke. RESULTS: Four hundred and thirty-three patients were identified and classified as having cerebral infarct, intra-parenchymal haemorrhage or subarachnoid haemorrhage. There were 414 patients who had CT scans and 19 had MRI scans. Within and across genders, over 80% suffered infarcts with no significant statistical difference between male and female patients. Subarachnoid haemorrhage was the least frequent subtype and occurred in younger patients. CONCLUSION: The pattern of stroke subtypes seen in this population was similar to that of Australian and European cohorts of patients but differed from that reported in Asians. Ischaemic infarct was the most frequent stroke subtype followed by intra- parenchymal haemorrhage and subarachnoid haemorrhage. There was no gender predilection for any specific type of stroke.
OBJETIVO: Examinar el patrón de los subtipos de accidente cerebrovascular encontrados en las imágenes de TAC y MRI en el Hospital Universitario de West Indies (HUWI), Kingston, Jamaica. MÉTODO: Se realizó un examen retrospectivo de todos los pacientes con diagnóstico de accidente cerebrovascular, sometidos a evaluación mediante TAC o MRI, entre enero 2001 y diciembre 2004. Los datos fueron recogidos teniendo en cuenta la edad y el género del paciente, así como el tipo de accidente. RESULTADOS: Cuatrocientos treinta y tres (433) pacientes fueron identificados y clasificados como pacientes con un infarto cerebral, hemorragia intraparenquimal o hemorragia subaracnoidea (HSA). Hubo 414 pacientes examinados con TAC y 19 con MRI. Dentro de ellos, ambos géneros incluidos, más del 80% sufrió infartos sin que hubiese diferencias estadísticas significativas entre hombres y mujeres. La hemorragia subaracnoidea fue el tipo menos frecuente, y se produjo en pacientes jóvenes. CONCLUSIÓN: El patrón de subtipos de accidente cerebrovascular en esta población fue similar al de cohortes de pacientes australianos y europeos, pero diferente al reportado para los asiáticos. El infarto isquémico fue el subtipo de accidente cerebrovascular más frecuente, seguido por la hemorragia intraparenquimal y la hemorragia subaracnoidea. No hubo preferencia de géneros en relación con ninguno de los tipos específicos de accidente cerebrovascular.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Young Adult , Cerebral Hemorrhage/diagnosis , Cerebral Infarction/diagnosis , Stroke/classification , Subarachnoid Hemorrhage/diagnosis , Age Distribution , Cerebral Hemorrhage/epidemiology , Cerebral Infarction/epidemiology , Confidence Intervals , Jamaica/epidemiology , Logistic Models , Magnetic Resonance Imaging , Multivariate Analysis , Odds Ratio , Retrospective Studies , Sex Distribution , Stroke/epidemiology , Stroke/etiology , Subarachnoid Hemorrhage/epidemiology , Tomography, X-Ray ComputedABSTRACT
OBJECTIVE: To examine the pattern of stroke subtypes found on Computed Tomography (CT), Magnetic Resonance Imaging (MRI) at the University Hospital of the West Indies (UHWI), Kingston, Jamaica. METHOD: A retrospective review was conducted for all patients diagnosed with stroke and who were subjected to CT or MRI evaluation at UHWI between January 2001 and December 2004. Data were collected for patient age and gender and type of stroke. RESULTS: Four hundred and thirty-three patients were identified and classified as having cerebral infarct, intra-parenchymal haemorrhage or subarachnoid haemorrhage. There were 414 patients who had CT scans and 19 had MRI scans. Within and across genders, over 80% suffered infarcts with no significant statistical difference between male and female patients. Subarachnoid haemorrhage was the least frequent subtype and occurred in younger patients. CONCLUSION: The pattern of stroke subtypes seen in this population was similar to that of Australian and European cohorts of patients but differed from that reported in Asians. Ischaemic infarct was the most frequent stroke subtype followed by intra- parenchymal haemorrhage and subarachnoid haemorrhage. There was no gender predilection for any specific type of stroke.
Subject(s)
Cerebral Hemorrhage/diagnosis , Cerebral Infarction/diagnosis , Stroke/classification , Subarachnoid Hemorrhage/diagnosis , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Cerebral Hemorrhage/epidemiology , Cerebral Infarction/epidemiology , Child , Child, Preschool , Confidence Intervals , Female , Humans , Jamaica/epidemiology , Logistic Models , Magnetic Resonance Imaging , Male , Middle Aged , Multivariate Analysis , Odds Ratio , Retrospective Studies , Sex Distribution , Stroke/epidemiology , Stroke/etiology , Subarachnoid Hemorrhage/epidemiology , Tomography, X-Ray Computed , Young AdultSubject(s)
Uterine Hemorrhage/diagnosis , Uterine Prolapse/diagnosis , Aged , Diabetes Mellitus , Diagnosis, Differential , Female , Humans , Hypertension , Hysterectomy , Leiomyoma , Postmenopause , Uterine Hemorrhage/pathology , Uterine Hemorrhage/surgery , Uterine Prolapse/pathology , Uterine Prolapse/surgeryABSTRACT
Intrathoracic extramedullary haematopoiesis is a rare entity encountered in patients with long standing anaemias such as thalassaemia and congenital spherocytosis. It is rare in patients with homozygous sickle cell disease; only 11 cases of intrathoracic and two cases of pelvic extramedullary haematopoiesis have been documented in the literature. We report the case of a 30-year old man with homozygous sickle cell disease with intrathoracic and pelvic extramedullary haematopoiesis, the first case to be documented from the Caribbean.
La hematopoyesis extramedular intratorácica es una entidad que raras veces se encuentra en pacientescon anemias de larga duración tales como la talasemia y la esferocitosis congénita. También es rara en pacientes que padecen la enfermedad de células falciformes homocigóticas. En la literatura se han documentado sólo 11 casos de hematopoyesis extramedular intratorácica y dos casos de hematopoyesis extramedular pélvica. Reportamos el caso de un hombre de 30 años de edad con la enfermedad decélulas falciformes homocigóticas con hematopoyesis extramedular intratorácica y pélvica el primercaso que se documenta en el Caribe.
Subject(s)
Humans , Male , Adult , Anemia, Sickle Cell/physiopathology , Hematopoiesis, Extramedullary/physiology , Bone Marrow/physiology , Fatal Outcome , Pelvic Bones , Thoracic VertebraeABSTRACT
Intrathoracic extramedullary haematopoiesis is a rare entity encountered in patients with long standing anaemias such as thalassaemia and congenital spherocytosis. It is rare in patients with homozygous sickle cell disease; only 11 cases of intrathoracic and two cases of pelvic extramedullary haematopoiesis have been documented in the literature. We report the case of a 30-year old man with homozygous sickle cell disease with intrathoracic and pelvic extramedullary haematopoiesis, the first case to be documented from the Caribbean.
Subject(s)
Anemia, Sickle Cell/physiopathology , Bone Marrow/physiology , Hematopoiesis, Extramedullary/physiology , Adult , Fatal Outcome , Humans , Male , Pelvic Bones , Thoracic VertebraeABSTRACT
Granulosa cell tumour with synchronous mature cystic teratoma is extremely rare and only eight cases are documented in the literature. Granulosa cell tumours are low-grade malignancies and need a close follow-up for recurrences which may be late. We report a case of granulosa cell tumour and mature cystic teratoma occurring synchronously in the same ovary in a post-menopausal woman.
Subject(s)
Granulosa Cell Tumor/pathology , Neoplasms, Multiple Primary/pathology , Ovarian Neoplasms/pathology , Teratoma/pathology , Diagnosis, Differential , Female , Granulosa Cell Tumor/surgery , Humans , Middle Aged , Neoplasms, Multiple Primary/surgery , Ovarian Neoplasms/surgery , Teratoma/surgeryABSTRACT
Granulosa cell tumour with synchronous mature cystic teratoma is extremely rare and only eight cases are documented in the literature. Granulosa cell tumours are low-grade malignancies and need a close follow-up for recurrences which may be late. We report a case of granulosa cell tumour and mature cystic teratoma occurring synchronously in the same ovary in a post-menopausal woman
Subject(s)
Humans , Female , Middle Aged , Granulosa Cell Tumor , Ovarian Neoplasms/pathology , Neoplasms, Multiple Primary/pathology , Teratoma/pathology , Granulosa Cell Tumor , Diagnosis, Differential , Ovarian Neoplasms/surgery , Neoplasms, Multiple Primary/surgery , Teratoma/surgerySubject(s)
Aneurysm, Ruptured/complications , Hematoma, Subdural, Acute/etiology , Intracranial Aneurysm/complications , Subarachnoid Hemorrhage/etiology , Adult , Aneurysm, Ruptured/diagnosis , Aneurysm, Ruptured/pathology , Autopsy , Female , Hematoma, Subdural, Acute/diagnosis , Hematoma, Subdural, Acute/pathology , Humans , Intracranial Aneurysm/diagnosis , Intracranial Aneurysm/pathology , Subarachnoid Hemorrhage/diagnosis , Subarachnoid Hemorrhage/pathology , Tomography, X-Ray ComputedABSTRACT
One per cent of all brain tumours and twenty per cent of meningiomas eventually develop an extracranial extension. The least common site is the neck. We report a case of malignant meningioma with extension into the neck of a 39-year-old male.
Subject(s)
Head and Neck Neoplasms/diagnosis , Meningeal Neoplasms/drug therapy , Meningioma/diagnosis , Adult , Brain/pathology , Fatal Outcome , Head and Neck Neoplasms/therapy , Humans , Magnetic Resonance Imaging , Male , Meningioma/therapy , Prognosis , Tomography, X-Ray ComputedABSTRACT
A case of tuberculous encephalopathy, a rare form of neuro-tuberculosis, is reported in a 16-year-old girl who had pulmonary tuberculosis and extensive cerebral demyelination. The clinical, laboratory and pathological features of this entity are highlighted and the pathogenesis discussed.
Subject(s)
Tuberculosis, Central Nervous System/diagnosis , Adolescent , Antibiotics, Antitubercular/therapeutic use , Brain/diagnostic imaging , Brain/pathology , Fatal Outcome , Female , Humans , Tomography, X-Ray Computed , Treatment Failure , Tuberculosis, Central Nervous System/drug therapy , Tuberculosis, Central Nervous System/etiology , Tuberculosis, Pulmonary/complicationsABSTRACT
Granulosa-theca cell tumours are ovarian neoplasms of low malignancy with hormone secreting potential, accounting for 2-3% of all ovarian cancers. They have an uncertain clinical course and a potential for late recurrence after surgical removal. Clinical features of a patient presenting with pulmonary metastases 21 years after removal of the primary tumour are described, along with a review of the management options.
Subject(s)
Granulosa Cell Tumor/secondary , Lung Neoplasms/secondary , Ovarian Neoplasms/pathology , Thecoma/secondary , Female , Follow-Up Studies , Granulosa Cell Tumor/pathology , Granulosa Cell Tumor/surgery , Humans , Lung Neoplasms/pathology , Lung Neoplasms/surgery , Middle Aged , Ovarian Neoplasms/surgery , Ovariectomy , Pneumonectomy , Thecoma/pathology , Thecoma/surgeryABSTRACT
Granulosa-theca cell tumours are ovarian neoplasms of low malignancy with hormone secreting potential, accounting for 2-3of all ovarian cancers. They have an uncertain clinical course and a potential for late recurrence after surgical removal. Clinical features of a patient presenting with pulmonary metastases 21 years after removal of the primary tumour are described, along with a review of the management options.
Subject(s)
Humans , Female , Middle Aged , Granulosa Cell Tumor , Ovarian Neoplasms/pathology , Lung Neoplasms/secondary , Bignoniaceae/secondary , Granulosa Cell Tumor , Ovarian Neoplasms/surgery , Lung Neoplasms/pathology , Lung Neoplasms/surgery , Ovariectomy , Pneumonectomy , Follow-Up Studies , Bignoniaceae/pathology , Bignoniaceae/surgeryABSTRACT
Inflammatory pseudotumour of the orbit is an unusual condition of unknown aetiology which rarely extends beyond the orbit. To our knowledge 19 cases with intracranial extension have been reported, none of which involved the pituitary fossa or sphenoid sinus. Most required cytotoxic agents, surgery or radiotherapy in addition to corticosteroids. We present a case of orbital pseudotumour with extension into the pituitary fossa, sphenoid sinus and cavernous sinuses with vascular compression. Marked clinical improvement occurred on steroid therapy alone.
Subject(s)
Orbital Pseudotumor/pathology , Adult , Brain/diagnostic imaging , Brain/pathology , Female , Humans , Orbital Pseudotumor/diagnostic imaging , RadiographyABSTRACT
A case of angiomyofibroblastoma of the vulva in a 23-year-old woman is presented. Clinical, histological and immunohistochemical features as well as the differential diagnosis and prognosis of this rare but distinct entity are discussed. Only about 65 cases are documented in the literature and to our knowledge this is the first case to be reported from the Caribbean.
Subject(s)
Angiomyoma/diagnosis , Fibroma/diagnosis , Vulvar Neoplasms/diagnosis , Adult , Angiomyoma/pathology , Diagnosis, Differential , Female , Fibroma/pathology , Humans , Vulva/pathology , Vulvar Neoplasms/pathologyABSTRACT
Inflammatory pseudotumour of the orbit is an unusual condition of unknown aetiology which rarely extends beyond the orbit. To our knowledge 19 cases with intracranial extension have been reported, none of which involved the pituitary fossa or sphenoid sinus. Most required cytotoxic agents, surgery or radiotherapy in addition to corticosteroids. We present a case of orbital pseudotumour with extension into the pituitary fossa, sphenoid sinus and cavernous sinuses with vascular compression. Marked clinical improvement occurred on steroid therapy alone.
Subject(s)
Humans , Female , Adult , Orbital Pseudotumor , Brain/pathology , BrainABSTRACT
A case of angiomyofibroblastoma of the vulva in a 23-year-old woman is presented. Clinical, histological and immunohistochemical features as well as the differential diagnosis and prognosis of this rare but distinct entity are discussed. Only about 65 cases are documented in the literature and to our knowledge this is the first case to be reported from the Caribbean.