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Clin Rheumatol ; 27(1): 125-7, 2008 Jan.
Article in English | MEDLINE | ID: mdl-17674118

ABSTRACT

Ocular involvement in Churg-Strauss syndrome (CSS) is infrequent. We describe a case of a 50-year-old woman, with blood eosinophilia, involvement of the respiratory tract, skin, and peripheral nervous system, fulfilling the American College of Rheumatology criteria for CSS, who presented with left foot drop followed by left acute painless visual loss. Central retinal artery occlusion was diagnosed by fundoscopic findings (retinal whitening with a cherry-red spot). CSS was confirmed by sural nerve biopsy. Despite treatment with high-dose corticosteroids, cyclophosphamide, and anticoagulant therapy, visual acuity was not substantially improved. Acute blindness in CSS has been rarely described. Even more rarely, central retinal artery occlusion has been found to be the underlying cause of this infrequent clinical manifestation in CSS.


Subject(s)
Churg-Strauss Syndrome/complications , Retinal Artery Occlusion/etiology , Retinal Artery/pathology , Vision, Low/etiology , Anticoagulants/therapeutic use , Churg-Strauss Syndrome/drug therapy , Churg-Strauss Syndrome/pathology , Cyclophosphamide/therapeutic use , Drug Therapy, Combination , Female , Glucocorticoids/therapeutic use , Humans , Middle Aged , Ophthalmoscopy , Retinal Artery Occlusion/drug therapy , Retinal Artery Occlusion/pathology , Treatment Outcome , Vision, Low/drug therapy , Vision, Low/pathology
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