ABSTRACT
Two case-reports are presented to support the hypothesis that bronchiectasis may occasionally be associated with a partial deficiency of T lymphocyte functions. This deficiency would represent another etiology of the heterogenous sino-pulmonary syndrome of which several causes have been identified or postulated: immunoglobulin deficiency, alpha-1-antitrypsin deficiency, mucociliary abnormality, phagocytosis or bactericidia abnormalities, etc.
Subject(s)
Bronchiectasis/immunology , Immunity, Cellular , Immunologic Deficiency Syndromes/complications , T-Lymphocytes/immunology , Adult , Female , HumansABSTRACT
Eight years after subtotal thyroidectomy for thyroid carcinoma, a patient developped multiple metastasis in bones and liver with high radioiodine uptake. This patient had clinical and biological thyrotoxicosis with low iodine uptake in the cervical remaining thyroid tissue and TSH secretion was not stimulated by TRH. Administration of 240 millicuries of 131 I led to hypothyroidism, to clinical regression of liver metastasis and to disappearance of extra-cervical iodine uptake. Eleven similar case have been reported in the literature.