ABSTRACT
Lipid management is well established as an effective preventive and management tool for cardiovascular disease (CVD). Health claims regarding the cholesterol lowering benefits of garlic are widespread. However, the clinical trial data are inconsistent. The effect of two doses of a commercial garlic preparation on plasma lipids were evaluated, compared to a placebo, in moderately hypercholesterolemic adults (baseline low density lipoprotein cholesterol (LDL-C)=157. 4+/-18.7, mean+/-S.D.). Fifty-one adults, aged 51.8+/-8.3 years participated in a double-blind, placebo-controlled, parallel treatment trial conducted in an outpatient research clinic. They were randomized to a placebo or a garlic botanical blend providing 500 or 1000 mg dehydrated garlic powder/day (three groups, 16-18 subjects per group). Plasma lipids were assessed every 2 weeks for 12 weeks. The study was designed with sufficient power to detect a 10% relative decline in LDL-C. The absolute mean changes in LDL-C over 12 weeks were 0.0+/-4.3, +1.4+/-4.8, and -10.1+/-6.8 mg/dl for the placebo, half-dose and full-dose, respectively. In the full-dose group, the LDL-C decrease of 6.1% was not significantly different from the other groups (P=0.5). No significant differences were observed for total- or high-density lipoprotein cholesterol (HDL-C), or triacylglycerol levels. In conclusion, the garlic powder preparation used in this study among moderately hypercholesterolemic adults did not significantly effect plasma lipids levels. There was no indication of a graded affect by garlic dose over the range of 0, 500 and 1000 mg/day. A small (<10%) effect on LDL-C levels or a threshold effect requiring larger doses are not eliminated by this study.
Subject(s)
Garlic , Hypercholesterolemia/blood , Hypercholesterolemia/diet therapy , Lipids/blood , Plants, Medicinal , Adult , Dose-Response Relationship, Drug , Double-Blind Method , Female , Humans , Male , Middle Aged , Powders , Treatment FailureABSTRACT
Anthropometric dimensions of Indian housewives have been measured from the viewpoint of architectural and product design ergonomics. Altogether, 79 different body dimensions were measured on 147 urban housewives of age range varying between 21 to 56 years. The average stature and weight of Indian housewives as observed in this study were 153.2 cm (SD +/- 5.7) and 55.1 kg (SD +/- 9.7), respectively. Average values along with 5th and 95th percentile values for all measurements have been determined. Values were compared with other Indian studies. A correlation between the body height, weight, and other measurements were obtained with the help of a PDP 11/23 microcomputer. Based on the existing data ratio scale relationships between the body height and other measurements of Indian women were determined. An anthropometric data, pack is presently lacking; therefore, the findings herein can be used while determining household workplace layouts, evaluating area specifications, determining work-surface heights, clearances, reach, etc. A similar study on a larger population size for Indian women has been suggested for establishing national standards.
Subject(s)
Anthropometry , Adult , Female , Humans , India , Middle Aged , Posture , Sri LankaABSTRACT
1. The differentiation of the vertebral elements of the cervical region of the chick has been studied from 4 to 23 day age group counted from the day of the commencement of incubation. 2. From the histochemical tests it appears that chondrogenesis does not take place simultaneously in all the areas of the vertebra. 3. Histochemical changes usually follow histological differentiation. 4. The findings have been discussed in the light of inducing principles by the spinal cord.
