ABSTRACT
OBJECTIVES: To evaluate the cardiovascular and endocrine effects of childhood obesity as well as prevalence of metabolic syndrome associated with it. METHODS: 49 obese and overweight children aged between 6 and 11 years as study group and 45 healthy non-obese controls of same age were selected for the study. Both the groups were evaluated for height, weight, BMI, waist circumference, blood pressure, fasting serum lipid fractions, insulin level, fasting and post-prandial blood glucose and C-reactive protein. Screening for metabolic syndrome was performed following most acceptable criteria. RESULTS: The study group children had significantly higher blood pressure, altered lipid fractions and high C-reactive Protein. Criteria-wise insulin resistance, hypertriglyceridemia and low high density lipoprotein also were found at significantly higher rate among obese children. The metabolic syndrome existed at a high prevalence of 14.1% in the study group. CONCLUSIONS: Obesity in childhood causes cardiovascular and endocrine dysregulation with onset of insulin resistance and metabolic syndrome even in absence of significant evidence of hypertension and type 2 diabetes mellitus in this age group.
Subject(s)
Metabolic Syndrome/epidemiology , Obesity/epidemiology , Case-Control Studies , Child , Cross-Sectional Studies , Female , Humans , India/epidemiology , Male , Metabolic Syndrome/prevention & control , Obesity/prevention & control , Prevalence , Risk FactorsABSTRACT
Screening of women of child bearing age among the tribal and rural population of different north eastern and eastern states of India was performed. More than 50% of women in some areas were found to have anemia. As part of the study nutritional supplementation was given to a proportion of the anemic population, comparing the effects of Spirulina, a compound containing vitamins and micronutrients and an iron-folic acid-B12 supplement. Follow-up of the cases was done over a period of one year and the impact of supplementation and a comparison of the two compounds made.
Subject(s)
Anemia/epidemiology , Anemia/prevention & control , Dietary Supplements , Micronutrients/administration & dosage , Adolescent , Adult , Anemia/blood , Female , Folic Acid/administration & dosage , Follow-Up Studies , Geography , Hemoglobins/analysis , Humans , Incidence , India/epidemiology , Iron, Dietary/administration & dosage , Mass Screening , Middle Aged , Outcome Assessment, Health Care , Population Groups , Pregnancy , Pregnancy Complications/diagnosis , Pregnancy Complications/epidemiology , Pregnancy Complications/prevention & control , Rural Population , Vitamin B 12/administration & dosage , Vitamins/administration & dosage , Young AdultABSTRACT
Chronic fatigue syndrome or myalgic encephalomyelitis in children and adolescents is still poorly understood. The provisional diagnostic criteria and the concept are depicted here. The treatment modalities and prognosis for the disease are yet inconsistent.