ABSTRACT
Forty nine cases of chronic liver disorders were studied for cutaneous manifestations. More than half of these (57.1%) cases revealed cutaneous changes. Common cutaneous manifestations were prominent dilated veins on abdomen (28.6%), icterus (20.1%), clubbing of nails (16.3%), ichthyosis (12.2%), hyperpigmentation (12.2%), pruritus (8.2%), gynaecomastia (8.2%) and spider naevi (6.1). Less common cutaneous manifestations included palmar erythema, telangiectasia, leuconychia, loss of body hair and acneiform eruptions in 4.1 per cent cases each and striae distense, purpura and pellagra in 2.0 per cent cases each.
ABSTRACT
Forty six cases of chronic liver disorders with and without cutaneous manifestations were studied for abnormalities of liver function tests. 27 cases were associated with cutaneous manifestations and 19 cases without cutaneous manifestations. A higher serum bilirubin level was seen in all cases with cutaneous manifestations. Serum bilirubin was significantly high (P<0.05) in patients of chronic active hepatitis with cutaneous manifestations. Serum alkaline phosphatase and serum glutamic pyruvic transaminase (SGPT) levels were significantly high in chronic active hepatitis and alcoholic liver disease without cutaneous manifestations respectively.
