ABSTRACT
INTRODUCTION: A key to successful patient outcomes following knee procedures like total knee arthroplasty (TKA) is achieving normal knee alignment. Normal mechanical balance in the joints must be restored in order to lessen the failure rate of TKA, and precise assessment of lower extremity alignment and component location is thought to be the primary determinant of a good clinical outcome over the long term. OBJECTIVE: The aim of this study was to assess the early functional and clinical outcomes of TKA by analyzing post-operative mechanical axis and Knee Society Score (KSS) data. The study also aimed to investigate the importance of achieving neutral mechanical alignment in TKA for long-term results. METHODS: A prospective and retrospective observational study was conducted, involving 40 patients with primary osteoarthritis who underwent bilateral or unilateral TKA. Demographic information, pre-operative comorbidities, knee abnormalities, and radiographic assessment were collected. Post-operative mechanical axis and implant placement were evaluated using CT scanograms. Clinical and functional assessments were performed using the Knee Society Score at regular intervals. The KSS scores were obtained at six-month intervals following surgery. The scores were categorized as excellent, very good, good, fair, or poor based on predefined criteria. RESULTS: A total of 47 knees from 40 patients were analyzed. The mean age of the study population was 65.6 years. Female patients accounted for 67.5% of the sample. The majority of patients (57.4%) achieved an excellent KSS score, followed by very good (25.5%) and good (17%) scores. The mean KSS score significantly improved from 177 points pre-surgery to 225 points post-surgery. The post-operative mechanical axis ranged from 1.1 degrees valgus to 9 degrees valgus, with a mean value of 3.5 degrees valgus. The range of motion improved from 10 to 90 degrees post-operatively, with a mean range of 0-110 degrees. CONCLUSION: This study suggests that total knee replacement surgery resulted in positive outcomes, with most patients achieving excellent or very good scores on the Knee Society scale. Proper axial and rotational alignment of the components during TKA enhanced functional outcomes and contributed to long-term clinical success. Restoration of neutral mechanical alignment and optimal component placement may lead to lower revision rates and increased durability after TKA. Further studies with larger sample sizes are needed to validate these findings.
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Background Heel discomfort and functional impairment are frequently caused by plantar fasciitis, and treating it can be extremely difficult for clinicians and occasionally have unfavorable clinical consequences. Recently, platelet-rich plasma (PRP) has been used as an alternative therapy for plantar fasciitis (PF) to reduce heel pain and improve functional restoration. We evaluated the current evidence concerning the efficacy and safety of PRP as a treatment for PF. Methodology This was a hospital-based prospective study on patients with plantar fasciitis with a symptom duration of six months or more with failed conservative therapy. All patients included in the study were assessed clinically and by a visual analog score (VAS) for heel pain, the Ankle-Hindfoot Scale (AHS) component of the American Orthopedic Foot and Ankle Society (AOFAS) and Foot and Ankle Ability Measure (FAAM) scores before injection, and at three weeks, three and six-months post-PRP treatment follow-up. Ultrasonography (USG) measurement of plantar fascia thickness was done pre-injection and at the six-month follow-up for clinical outcomes and any complications. Results The study included 25 patients with plantar fasciitis, with the majority (48%) in the age group of 21-30 years. Females accounted for 64% of the patients while males accounted for 36%. Most patients (56%) had a moderately active daily activity level. The study found that 16 patients had bilateral plantar fasciitis while nine had unilateral plantar fasciitis. Among the patients with bilateral plantar fasciitis, a total of 32 heels were affected while the 9 patients with unilateral plantar fasciitis had 9 affected heels. Most female patients (75%) had bilateral plantar fasciitis while most male patients (56%) had unilateral plantar fasciitis. Before PRP therapy, both male and female patients reported high pain scores on the VAS for both heels. However, after PRP infiltration, the VAS scores significantly decreased at three weeks, three months, and six months post-injection, indicating pain relief. The AOFAS hindfoot and ankle scores and FAAM scores showed improvement over the follow-up period. Both male and female patients experienced significant improvements in functional outcomes, with increases in AOFAS (p-value 0.45) and FAAM scores (p-value 0.31) at three weeks, three months, and six months post-injection compared to baseline. Statistical analysis revealed a significant decrease in pain scores (73% pain relief), as well as significant improvements in AOFAS scores with an average of 22.33 from baseline (mean = 67.75±9.7) to final follow-up (mean = 90.08±7.9) and FAAM scores with an average of 23.72 from baseline (mean = 49.38±5.2) to final follow-up (mean = 73.10±5.2) after PRP infiltration. Conclusion The outcomes of a single dosage of PRP injections demonstrate clinically and statistically substantial improvements in functional outcome scores, plantar fascia thickness evaluated by USG, and VAS scores for heel pain. According to the results of this study, local PRP injection is an effective treatment for chronic plantar fasciitis.
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Purpose: Despite the global efforts to improve organ donation, there is a demand-supply gap for organs in India. The only solution to meet this disparity is to improve deceased donor transplants in the country through victims of road accidents. The government has instituted several initiatives to achieve this goal. However, challenges and barriers continue to affect the organ donation process. The present study aims to document the motivating factors and obstacles in the decision of families to donate organs in Ahmedabad, Gujarat and their suggestions to improve the processes involved in organ donation. Patients and Methods: A qualitative exploratory study (in-depth interview) of ten relatives of deceased organ donors was conducted from Oct 2021 to Feb 2022. Interviews were audio recorded, and detailed notes were taken during the interview. Thematic analysis was done using ATLAS.ti version 8 software. Results: The significant motivators identified were family members' belief or conviction that it would help save the lives of others; a sense of moral obligation to do so as bodies of brain-dead persons can contribute to this noble goal, no use of the body after death, an extension of life, and being a role model for others. The challenges were mistrusting the organ donation process, fear of being responsible for any mishappening, and feeling of shock. The suggestions to improve organ donation included awareness creation, simplifying the legal process for accidental deaths, providing benefits to the donor family, and a system for identifying potential donors and their counselling. Conclusion: The present study reflects the need for a more comprehensive awareness campaign to generate awareness and remove the misconception about organ donation in India. The findings of the study can be helpful for policymakers to amend the current organ donation process in India and improve the disequilibrium of demand and supply of deceased donations in India.
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BACKGROUND: Objective of the study was to evaluate and compare psychometric properties such as validity, reliability, floor ceiling effects and interpretability of the modified Harris Hip Score (mHHS) and the Forgotten Joint Score (FJS) in patients undergoing bipolar hemiarthroplasty for femoral neck fracture in Indian patients, because this has not been done before. METHODS: This observational study consisted of 40 consecutively operated patients. Construct validity and reliability were evaluated using correlation coefficient and Intraclass correlation coefficient (ICC), respectively. Interpretability was evaluated by describing mean and standard deviation of mHHS and FJS in five subgroups of patients based on their response to the global rating questions and assessment. RESULTS: The mean follow-up duration was 15.7 months ± 10.4. There was very high correlation between mHHS and FJS (r = 0.92, p < 0.0001) suggesting convergent construct validity. The results of correlation coefficient were 100% and 66.7% in accordance with the pre-formulated hypotheses for mHHS and FJS, respectively. mHHS and FJS demonstrated adequate construct validity and inadequate construct validity, respectively. The ICC value for mHHS and FJS was 0.80 (p = 0.005) {adequate reliability} and 0.34 (p = 0.06) {inadequate reliability}, respectively. Both mHHS and FJS-12 demonstrated acceptable level of floor (0% for mHHS and 14.3% for FJS) and ceiling effects (12.5% for both mHHS and FJS). There was significant difference in the mHHS and FJS in the five subgroups of patients suggesting adequate interpretability. CONCLUSION: We recommend the use of the modified Harris Hip Score over the Forgotten Joint Score for functional outcome evaluation of Indian patients from rural setting undergoing bipolar hemiarthroplasty for femoral neck fracture.
