ABSTRACT
We report the case of a 69-year-old man, who presented in the UK with a short history of deteriorating vision and clinical features of bilateral atypical retinochoroiditis, after travelling to South America. Vitreous samples demonstrated Toxoplasma gondii DNA by PCR. Serology tests demonstrated recent acquired Toxoplasma gondii infection with IgM antibodies. He responded well to treatment with trimethoprim-sulfamethoxazole, azithromycin and oral steroids.This case is a reminder of the global importance of Toxoplasma related eye disease, and its uncommon bilateral severe presentation in a returning traveller, where the risk factors were age and the route of infection likely to be a virulent parasite oocyst from vegetables or water rather than undercooked meat or direct contact with cats.
Subject(s)
Toxoplasmosis, Ocular/diagnosis , Travel-Related Illness , Age Factors , Aged , Anti-Bacterial Agents/therapeutic use , Azithromycin/therapeutic use , Fundus Oculi , Glucocorticoids/therapeutic use , Humans , Male , South America , Tomography, Optical Coherence , Toxoplasmosis, Ocular/drug therapy , Toxoplasmosis, Ocular/pathology , Toxoplasmosis, Ocular/transmission , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use , United KingdomSubject(s)
Acrylamides/adverse effects , Aquaculture , Cnidarian Venoms/adverse effects , Keratitis/chemically induced , Occupational Diseases/chemically induced , Animals , Anthozoa , Anti-Bacterial Agents/therapeutic use , Drug Therapy, Combination , Female , Glucocorticoids/therapeutic use , Humans , Keratitis/diagnosis , Keratitis/drug therapy , Middle Aged , Occupational Diseases/diagnosis , Occupational Diseases/drug therapy , Ofloxacin/therapeutic use , Prednisolone/therapeutic useSubject(s)
Corneal Diseases/etiology , Epithelium, Corneal/pathology , Eyelashes/transplantation , Hair Follicle/transplantation , Organ Transplantation/adverse effects , Trichiasis/etiology , Adult , Alopecia/surgery , Corneal Diseases/diagnosis , Corneal Diseases/surgery , Female , Hair Removal , Humans , Transplantation, Autologous , Trichiasis/diagnosis , Trichiasis/surgeryABSTRACT
PURPOSE: Despite the increasing use of antivascular endothelial growth factors (anti-VEGF), photodynamic therapy (PDT) with Verteporfin is still considered the gold standard treatment of subfoveal and juxtafoveal classic choroidal neovascularization (CNV). METHODS: Case report. RESULTS: The authors report a case of a 72-year-old man who developed choroidal nonperfusion and significant subretinal fluid formation with associated severe visual loss following PDT of predominantly classic juxtafoveal CNV. CONCLUSIONS: Although reported separately, these two complications have not been previously reported to occur in association after PDT treatment of classic CNV and may represent exaggeration of normal events occurring after PDT.
