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1.
Eur J Ophthalmol ; 34(1): 71-78, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37700603

ABSTRACT

PURPOSE: To evaluate the safety and efficacy of the surgery of intracorneal ring segment implantation with 320° of arc (320-ICRS) in patients with advanced keratoconus stage IV and maximum keratometry (Kmax) above 60 D. METHODS: A prospective, interventional case series study evaluating 25 eyes of 19 patients with keratoconus stage IV and Kmax > 60D in which 320-ICRS were implanted using VisuMax® femtosecond. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), keratometric values (mean - mean-K, flat - K1, and steep - K2), maximum keratometry (Kmax), tomographic astigmatism, refractive astigmatism and asphericity (Q) were assessed preoperatively and at 3, 6 and 12 months after the procedure. RESULTS: The UDVA improved from 1.03 ± 0.28 LogMAR (20/200) to 0.54 ± 0.21 LogMAR (20/60), (p < 0.001), the CDVA (with glasses) improved from 0.63 ± 0.29 LogMAR (20/80) to 0.31 ± 0.16 LogMAR (20/40),(p = 0.004), K1 reduced from 54.41 ± 4.46 D to 49.36 ± 4.11 D (p < 0.001), K2 reduced from 61.15 ± 4.37 D to 53.715 ± 4.05 D, (p < 0.001), mean-K reduced from 57.55 ± 4,17 D to 51.44 ± 3,94 D (p < 0.001), Kmax reduced from 69.80 ± 8.20 D to 63.43 ± 6.31 D (p < 0.001) and asphericity (Q) changed from -1.57 ± 0.35 to -0.77 ± 0.56 (p < 0.001). A total of 89.9% patients reached BCVA wearing scleral contact lens  0.2 LogMAR(20/25). CONCLUSION: 320-ICRS to treat advanced keratoconus appears to be an efficacious and safe procedure, being a surgical alternative to delay or even prevent corneal transplantation.


Subject(s)
Astigmatism , Corneal Transplantation , Keratoconus , Humans , Keratoconus/surgery , Prosthesis Implantation/methods , Astigmatism/surgery , Prospective Studies , Corneal Stroma/surgery , Treatment Outcome , Corneal Topography , Refraction, Ocular , Prostheses and Implants
2.
J Refract Surg ; 35(10): 673-683, 2019 Oct 01.
Article in English | MEDLINE | ID: mdl-31610009

ABSTRACT

PURPOSE: To compare the outcomes of intracorneal ring segments (ICRS) implantation in keratoconic eyes with a similar tomographic pattern, using two different manufacturers' nomograms for surgical planning. METHODS: ICRS were implanted alternately in patients with the same tomographic pattern of keratoconus divided into two groups according to the surgical planning proposed by the ICRS manufacturers (Keraring, Mediphacos, Belo Horizonte, Brazil, and Ferrara Ring, AJL Ophthalmics, Vitoria, Spain). Visual, refractive, keratometric, corneal aberrometry, and optical quality changes were evaluated during a 6-month follow-up. Corneal and manifest refractive astigmatic changes were also analyzed using the double-angle polar plot and the Alpins vectorial method through the following components: target induced astigmatism, surgically induced astigmatism, difference vector, correction index, angle of error, index of success, flattening effect, and torque. RESULTS: After ICRS implantation, both groups showed significant improvement (P < .05) in visual and keratometric data. Corneal aberrometric changes and optical quality improvement were also statistically significant in both groups, except for trefoil (P > .05 in all intervals). The Alpins method analysis showed a better performance in the Keraring group, but with no statistically significant difference between groups (P > .05). Comparison between groups showed a statistically significant difference only in tomographic astigmatism in double-angle polar plot analysis (P = .03), with more significant improvement in the Keraring group. CONCLUSIONS: Both manufacturers' nomograms resulted in statistically significant improvement in most of the parameters analyzed, with greater correction of corneal tomographic astigmatism in the group operated on according to the spherical equivalent/tomographic astigmatism nomogram. [J Refract Surg. 2019;35(10):673-683.].


Subject(s)
Corneal Stroma/surgery , Keratoconus/surgery , Nomograms , Prostheses and Implants , Prosthesis Implantation , Aberrometry , Adolescent , Adult , Child , Corneal Topography , Female , Humans , Keratoconus/physiopathology , Male , Prospective Studies , Refraction, Ocular/physiology , Visual Acuity/physiology , Young Adult
3.
Rev. bras. oftalmol ; 75(6): 470-472, nov.-dez. 2016. ilus
Article in English | LILACS | ID: biblio-829985

ABSTRACT

ABSTRACT One patient with a history of trabeculectomy with Mitomicin C 0.02%, but no history of systemic disorders, exhibited unilateral corneal lipid infiltrates, together with deep stromal vascularization. She was treated with a bevacizumab injection and penetrating keratoplasty. No sign of recurrence was noted after one year post-operative.


RESUMO Um paciente com história de trabeculectomia com Mitomicina C 0,02%, sem doenças sistêmicas pré-existentes, apresentou infiltrado lipídico corneano unilateral associado à vascularização intraestromal profunda. Injeção subconjuntival de Bevacizumabe foi realizada e posterior ceratoplastia penetrante. Não houve sinais de recorrência em um ano.


Subject(s)
Humans , Female , Middle Aged , Bevacizumab/therapeutic use , Cornea/metabolism , Keratoplasty, Penetrating , Mitomycin , Phospholipids/metabolism , Trabeculectomy
4.
Rev. bras. oftalmol ; 74(3): 183-185, May-Jun/2015. graf
Article in English | LILACS | ID: lil-764233

ABSTRACT

The purpose of the authors is to show clinical findings of a patient with benign concentric annular macular dystrophy, which is an unusual condition, and part of the “bull’s eye” maculopathy differential diagnosis. An ophthalmologic examination with color perception, fluorescein angiography, and ocular electrophysiology was performed.


O objetivo dos autores é detalhar o quadro clínico de um paciente com distrofia macular anular concêntrica benigna, quadro raro, que compõe o diagnóstico diferencial das maculopatias em alvo. Realizou-se avaliação oftalmológica com auxílio de testes de percepção de cores, angiofluoresceinografia e eletrofisiologia ocular.


Subject(s)
Humans , Male , Adult , Color Perception , Retinal Diseases/diagnosis , Electrophysiology , Fluorescein Angiography , Macula Lutea/pathology , Diagnosis, Differential
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