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1.
Rev. enferm. UFPE on line ; 10(3): 969-976, mar. 2016. tab
Article in English, Portuguese | BDENF - Nursing | ID: biblio-1031564

ABSTRACT

Objetivo: identificar os diagnósticos de enfermagem do domínio promoção da saúde em mulheres com osteoporose no climatério à luz do conceitual de Orem. Método: estudo descritivo, do tipo transversal, realizado com 35 mulheres com diagnóstico de osteoporose secundária à menopausa, na faixa etária de 45 aos 65 anos, atendidas em um centro de especialidades do município de Imperatriz (MA), Brasil. Resultados: os principais diagnósticos identificados foram: Disposição para autocontrole da saúde melhorado (94,2%) e Estilo de vida sedentário (83%). Conclusão:os achados demostraram que a identificação das necessidades de cuidados favorece a implantação de intervenções específicas, contribuindo para a qualidade da assistência de enfermagem às mulheres com osteoporose.(AU)


Objective: to identify the nursing diagnoses of the domain health promotion in women with osteoporosis during menopause in the light of Orem's concept. Method: descriptive, cross-sectional study conducted with 35 women diagnosed with osteoporosis secondary to menopause, aged from 45 to 65 years old, treated at a specialty center in the city of Imperatriz (MA), Brazil. Results: the main identified diagnoses were: Readiness for enhanced self-health management (94.2%) and Sedentary lifestyle (83%). Conclusion: the findings demonstrated that the identification of care needs favors the implementation of specific interventions, contributing to the quality of nursing care to women with osteoporosis.(AU)


Objetivo: identificar los diagnósticos de enfermería del dominio promoción de la salud en mujeres con osteoporosis en el climaterio con base en el concepto de Orem. Método: estudio descriptivo, del tipo transversal, realizado con 35 mujeres con diagnóstico de osteoporosis secundaria a la menopausia, en la edad de 45 a 65 años, atendidas en un centro de especialidades del municipio de Imperatriz (MA), Brasil. Resultados: los principales diagnósticos identificados fueron: Disposición para autocontrol de la salud mejorado (94,2%) y Estilo de vida sedentario (83%). Conclusión: los hallados demostraron que la identificación de las necesidades de cuidados favorece la implantación de intervenciones específicas, contribuyendo para la calidad de la asistencia de enfermería a las mujeres con osteoporosis.(AU)


Subject(s)
Humans , Female , Adult , Aged , Self Care , Nursing Diagnosis , Osteoporosis , Health Promotion , Climacteric , Epidemiology, Descriptive
2.
Toxicol Mech Methods ; 24(8): 603-7, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25141890

ABSTRACT

BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate genotoxicity and mutagenicity in peripheral blood and buccal mucosal cells in mucopolysaccharidosis (MPS) I, II or VI patients. METHODS: A total of 12 patients with MPS type I, II and VI attended at the Institute of Genetics and Inborn Errors of Metabolism treated with enzyme replacement therapy (ERT) and 10 healthy control volunteers were included in this study. Mechanically exfoliated cells from cheek mucosa (left and right side) were used to micronucleus test and single cell gel (comet) assay in peripheral blood cells. RESULTS: The results of this study detected the presence of genetic damage in peripheral blood for all individuals with MPS treated with ERT, regardless of type of MPS as depicted by tail moment results. In addition, an increased number of micronucleated cells were found in buccal cells of MPS type II patients. It was also observed an increase of other nuclear alterations closely related to cytotoxicity as depicted by the frequency of pyknosis, karyolysis and karyorrhexis in buccal mucosa cells of MPS VI patients (p < 0.05). CONCLUSION: Taken together, such results demonstrate that metabolic alterations induced by the enzymatic deficiency characteristic of MPS associated with ERT therapy can induce genotoxicity and mutagenicity in peripheral blood and buccal mucosa cells, respectively. This effect appears to be more pronounced to MPS II.


Subject(s)
Cell Nucleus/pathology , Chromatin/pathology , DNA Damage , DNA Fragmentation , Mucopolysaccharidosis II/pathology , Mucopolysaccharidosis IV/pathology , Mucopolysaccharidosis I/pathology , Adolescent , Adult , Blood Cells/pathology , Brazil , Cell Nucleus Shape , Child , Child, Preschool , Cytogenetic Analysis , Enzyme Replacement Therapy , Female , Humans , Male , Mouth Mucosa/pathology , Mucopolysaccharidosis I/blood , Mucopolysaccharidosis I/genetics , Mucopolysaccharidosis I/therapy , Mucopolysaccharidosis II/blood , Mucopolysaccharidosis II/genetics , Mucopolysaccharidosis II/therapy , Mucopolysaccharidosis IV/blood , Mucopolysaccharidosis IV/genetics , Mucopolysaccharidosis IV/therapy , Young Adult
3.
Rev. enferm. UFPE on line ; 8(3): 649-653, mar.2014. ilus
Article in Portuguese | BDENF - Nursing | ID: biblio-1033696

ABSTRACT

Objetivo: avaliar a percepção da ansiedade no paciente oncológicos por meio de escala padronizada evalidada para língua portuguesa. Método: estudo quantitativo, com 75 pacientes, com mais de um ciclo dequimioterapia. Os dados foram coletados com questionário e tratados pelo programa “Statistics for Windows”versão 7. O projeto de pesquisa foi aprovado pelo Comitê de Ética em Pesquisa, Protocolo 061/11).Resultados: dos 75 pacientes, o câncer de mama (50%) foi prevalente nas mulheres e próstata (15,7%) noshomens. Em relação à ansiedade, a maioria dos pacientes não apresentou ansiedade (66,6%), muitoprovavelmente se deva ao tratamento já iniciado e a esperança de cura por parte deles. Conclusão: osresultados mostram a importância da análise e compreensão da ansiedade em pacientes oncológicos e de seobservar que estes experimentam graus e caracteres de ansiedade variáveis acarretando em alterações emdiversos níveis gerando estresse tanto para ele quanto para a família.


Subject(s)
Male , Female , Humans , Anxiety , Neoplasms , Drug Therapy , Epidemiology , Cross-Sectional Studies
4.
Rev. dor ; 13(1): 45-49, jan.-mar. 2012. tab
Article in Portuguese | LILACS | ID: lil-624930

ABSTRACT

JUSTIFICATIVA E OBJETIVOS: O câncer em estágio avançado geralmente causa dor cuja intensidade varia com a sua localização, o grau de evolução e o tipo de tratamento. O objetivo deste estudo foi avaliar a dor em pacientes oncológicos que estão ou estiveram em tratamento quimioterápico em hospital no município de Imperatriz-MA. MÉTODO: Os dados foram coletados a partir de questionários contendo identificação, doenças pré-existentes, manifestações clínicas, a escala numérica de avaliação da dor e o questionário McGill. RESULTADOS: Observou-se que o câncer de mama (50%) e o câncer de pulmão (38,8%) foram respectivamente os mais prevalentes no gênero feminino e masculino. A dor foi relatada por 58,6% dos pacientes no momento da entrevista ou na semana da mesma, sendo os locais mais relacionados: membros superiores e inferiores (18,5%) e tórax (11,1%). A intensidade média da dor avaliada pela escala numérica foi 6,7 ± 1,83, o que pode ser caracterizada dor de moderada intensidade e pelo questionário McGill, foi caracterizada como sensorial. CONCLUSÃO: A dor de moderada intensidade e de caráter sensorial estava presente na maioria dos pacientes oncológicos levando-os a perda de energia para executar atividades diárias.


BACKGROUND AND OBJECTIVES: Advanced cancer usually causes pain, the intensity of which depends on site, level of evolution and type of treatment. This study aimed at evaluating pain in cancer patients who are or have been treated with chemotherapy in a hospital from the city of Imperatriz/MA. METHOD: Data were collected through questionnaires with identification, pre-existing diseases, clinical manifestations, numerical pain evaluation scale and McGill questionnaire. RESULTS: It has been observed that breast cancer (50%) and lung cancer (38.8%) were the most prevalent, respectively, among females and males. Pain was reported by 58.6% of patients during the interview or during the interview's week and most frequently reported sites were upper and lower limbs (18.5%) and chest (11.1%). Mean pain intensity evaluated by the numerical scale was 6.7 ± 1.83, which may be considered moderate pain and sensory pain by McGill questionnaire. CONCLUSION: Moderate and sensory pain was present in most cancer patients and has led to loss of energy to perform daily activities.


Subject(s)
Neoplasms , Nursing , Pain , Pain Measurement
5.
Cell Biochem Funct ; 30(4): 293-6, 2012 Jun.
Article in English | MEDLINE | ID: mdl-22287211

ABSTRACT

The aim of this study was to investigate the effects of exercise in multiple organs of rats treated with doxorubicin. Male adult Wistar rats were distributed into the following groups: sedentary + NaCl; exercise + NaCl; sedentary + doxorubicin; and exercise + doxorubicin. Animals were sacrificed 2 days following injections. Central fragments from heart, liver, and kidney were collected and minced in 0.9% NaCl being cellular suspensions used for the single-cell gel (comet) assay. The results showed that exercise was able to prevent genotoxicity induced by doxorubicin in heart cells. By contrast, exercise was not able to prevent genotoxicity induced by doxorubicin in liver cells. The same occurred to kidney cells, i.e. no statistically significant differences (p > 0.05) were found when compared with groups not exposed to doxorubicin. Taken together, our results support the idea that exercise could contribute to the protective effect against genotoxicity induced by doxorubicin in heart cells.


Subject(s)
Doxorubicin/toxicity , Physical Conditioning, Animal , Animals , Comet Assay , DNA Damage/drug effects , Heart/drug effects , Kidney/drug effects , Liver/drug effects , Male , Rats , Rats, Wistar
6.
Gen Dent ; 55(3): 224-7, 2007.
Article in English | MEDLINE | ID: mdl-17511366

ABSTRACT

Adenocarcinoma of the lung that metastasizes to the mandible is very uncommon; only a few cases have been described in the English-language literature. This article presents a metastasis from adenocarcinoma of the lung affecting the mandible of a 64-year-old woman, in which the first discovered metastatic lesion was detected before the primary tumor. The immunoreactivity for human thyroid transcription factor-1 (TTF-1) in the oral lesion was essential for determining the site and type of the primary tumor, as the patient showed no clinical or radiographic evidence of a tumor in the thyroid gland. After the primary tumor in the lung was diagnosed, radiotherapy and chemotherapy were initiated; unfortunately, the patient died two months after the start of treatment. This article emphasizes the importance of a well-conducted examination for diagnosing metastatic oral lesions.


Subject(s)
Adenocarcinoma/secondary , Lung Neoplasms/diagnosis , Mandibular Neoplasms/secondary , Adenocarcinoma/pathology , Fatal Outcome , Female , Homeodomain Proteins/analysis , Humans , Lung Neoplasms/pathology , Middle Aged , Nuclear Proteins/analysis , Skull Neoplasms/secondary , Thyroid Nuclear Factor 1 , Transcription Factors/analysis
7.
J. bras. med ; 89(1): 45-50, jul. 2005.
Article in Portuguese | LILACS | ID: lil-424270

ABSTRACT

A incontinência pigmentar é uma doença genética dominante ligada ao X, com comprometimento neurológico, oftalmológico, dental e cutânea. Este trabalho apresenta aspectos etiológicos e clínicos, tratamento e prognóstico


Subject(s)
Humans , Incontinentia Pigmenti/etiology , Incontinentia Pigmenti/physiopathology , Sex Chromosome Aberrations , X Chromosome
8.
J. bras. med ; 88(5): 31-34, maio 2005.
Article in Portuguese | LILACS | ID: lil-561182

ABSTRACT

O ceratoacantoma é uma neoplasia benigna de crescimento rápido, podendo sofrer regressão espontânea sem qualquer tipo de tratamento. Acomete principalmente pacientes idosos em locais do corpo que sofreram exposião crônica à luz solar, como a face o os membros superiores. Clinicamente se caracteriza por um nódulo crateriforme, com uma depressão central preenchida por ceratina. Histologicamente apresenta hiperceratose e acantose, onde as células epiteliais apresentam características que se assemelham ao carcinoma espinocelular, como atipia celular, mitoses atípicas, disceratose e formação de pérolas de ceratina. O diagnóstico de ceratoacantoma é baseado mais na arquitetura do que nas características celulares. O tratamento preconizado é a remoção cirúrgica. Devido à semelhança entre o ceratoacantoma e o carcinoma espinocelular, uma discussão a respeito de métodos de diagnóstico e a real distinção entre essas duas entidades tem sido realizada.


The keratoacanthoma is a common tumor of the skin that displays rapid growth and usually involutes spontaneously. Clinically is characterized by a crateriform nodule with a central keratinous core that often appears on sun-exposed regions of white person of middle age or older. The histopathological findings are hyperkeratosis, acanthosis, and this epidermal strands may be carcinoma-like, containing atypical-appearing squamous cells with multiple mitotic figures, dyskeratosis, marked pleomorphism or anaplasia. In short, the diagnosis of keratoacanthoma is based on its architecture rather than its cytological features. The treatment of choise for keratoacanthoma is the complete conservative excision. The distinction between squamous cell carcinoma and keratoacanthoma has been a matter of discussion, and a lot of techniques have been used to try to find a differential diagnosis between these two lesions.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Keratoacanthoma/surgery , Keratoacanthoma/classification , Keratoacanthoma/diagnosis , Keratoacanthoma/etiology , Keratoacanthoma/physiopathology , Keratoacanthoma/therapy , Carcinoma, Squamous Cell , Diagnosis, Differential , Fluorouracil/therapeutic use , Sunlight/adverse effects , Ultraviolet Rays/adverse effects
9.
J. bras. med ; 88(4): 29-32, abr. 2005.
Article in Portuguese | LILACS | ID: lil-540291

ABSTRACT

Os autores realizaram uma revisão da literatura sobre dermatite herpetiforme (DH), apresentando os acometimentos cutâneos e bucais. Tal enfermidade, de provável etiologia auto-imune, consiste de uma doença crônica vesicobolhosa caracterizada clinicamente por pápulas e vesículas pruriginosas. Microscopicamente, através de fluorescência, pode ser observada a presença de depósito granular de IgA ao longo de membrana basal. Há associação entre pacientes portadores de DH e a sensibilidade ao glúten, esse achado também encontrado na doença celíaca. O tratamento recomendado para essa enfermidade é medicamentoso associado a uma dieta livre de glúten. Neste artigo discorre-se sobre etiologia, relações com enteropatia, influência do glúten, tratamento e diagnósticos diferenciais.


Subject(s)
Male , Female , Dermatitis Herpetiformis/diagnosis , Dermatitis Herpetiformis/physiopathology , Dermatitis Herpetiformis/therapy , Celiac Disease/complications , Chronic Disease , Glutens/adverse effects
10.
Braz Dent J ; 14(3): 220-2, 2003.
Article in English | MEDLINE | ID: mdl-15057401

ABSTRACT

This work describes the knowledge and experience of dentists about cardiopulmonary resuscitation (CPR). A total of 182 dentists from São Paulo State, Brazil were interviewed: 59% judged themselves able to define CPR, although only 46% had a correct concept; 54% believed himself to be able to perform CPR, however, none of them referred to have received practical training in CPR; 3% of the interviewed professionals mentioned the occurrence of cadiopulmonary arrest in their dental office. It was concluded that dental surgeons in Brazil should be better trained for medical emergencies that can occur in the dental office.


Subject(s)
Cardiopulmonary Resuscitation/education , Dentists , Education, Dental , Attitude of Health Personnel , Brazil , Clinical Competence , Dentists/psychology , Heart Arrest/diagnosis , Heart Arrest/therapy , Humans , Self Concept
11.
Braz. dent. j ; 14(3): 220-222, 2003. tab
Article in English | LILACS | ID: lil-356716

ABSTRACT

Este trabalho descreve o conhecimento e experiência dos cirurgiões dentistas em reanimação cárdio-respiratória (RCR). Foram entrevistados 182 cirurgiões dentistas do Estado de São Paulo, Brasil: 59 por cento julgava-se capaz de definir RCR, embora somente 46 por cento tivesse um conceito correto; 54 por cento acreditava ser capaz de realizar RCR, no entanto nenhum deles referiu ter recebido treinamento prático em RCR; 3 por cento dos entrevistados mencionou a ocorrência de parada cárdio-respiratória no consultório odontológico. Concluiu-se que os cirurgiões dentistas brasileiros deveriam ser melhor treinados em emergências médicas que podem ocorrer nos consultórios odontológicos.


Subject(s)
Humans , Cardiopulmonary Resuscitation/education , Dentists , Education, Dental , Attitude of Health Personnel , Brazil , Clinical Competence , Dentists/psychology , Heart Arrest/diagnosis , Heart Arrest/therapy , Self Concept
12.
Braz. dent. j ; 13(1): 49-52, jan.-abr. 2002.
Article in English | LILACS, BBO - Dentistry | ID: lil-554404

ABSTRACT

O herpes zoster (HZ) é uma doença virótica causada pelo Herpesvirus varicellae. Este estudo foi realizado para determinar fatores que desencadeiam a doença, bem como alterações sistêmicas e bucais em pacientes com HZ. A atmosfera foi composta por 30 pacientes com HZ e 100 pacientes com outras doenças (grupo controle - GC). Dos 30 pacientes com HZ, 13 eram do sexo masculino (43,3 por cento) e 17 do sexo feminino (56,7 por cento), com idades de 3 a 78 anos, média de 43,2. Os pacientes foram submetidos a exame clínico geral, dermatológico e bucal. Somente 50 por cento dos pacientes com HZ referiram estresse emocional, durante o início da doença. Observou-se investigação positiva para HIV em 3,7 por cento e para neoplasias malignas em 11,1 por cento dos pacientes. As lesões no grupo HZ se localizavam no tórax (68,3 por cento), face (20 por cento), membros inferiores (10 por cento) e membros superiores (6,7 por cento). Comprometimento bucal específico pelo HZ não foi encontrado. A presença da doença pode indicar neoplasia maligna não diagnosticada e/ou SIDA.


Subject(s)
Male , Female , Child, Preschool , Child , Adolescent , Adult , Middle Aged , Humans , Mouth Diseases/etiology , Herpes Zoster , Skin Diseases, Viral , Brazil
13.
Braz Dent J ; 13(1): 49-52, 2002.
Article in English | MEDLINE | ID: mdl-11870963

ABSTRACT

Herpes zoster (HZ) is a virotic disease caused by Herpesvirus varicellae. The objective of this study was to determine the factors that trigger the disease, and the systemic and oral alterations present in Brazilian patients with herpes zoster. A total of 30 patients with HZ and 100 control patients with other diseases were studied. Of the 30 patients with HZ, 13 were male (43.3%) and 17 were female (56.7%), with an average age of 43.2 (range 3-78). The patients were submitted to general clinical, dermatological and intraoral examinations. Only 50% of the HZ patients reported emotional stress at the onset of the disease. A total of 3.7% of the patients were positive for HIV and 11.1% for systemic malignant neoplasm. Cutaneous lesions were found on the thorax (68.3%), face (20%), lower limbs (10%) and upper limbs (6.7%). Specific oral involvement such as oral HZ was not found. The presence of the disease may indicate a non-diagnosed malignant neoplasm and/or association with AIDS.


Subject(s)
Herpes Zoster/complications , Mouth Diseases/etiology , Skin Diseases, Viral/complications , Adolescent , Adult , Aged , Brazil , Case-Control Studies , Chi-Square Distribution , Child , Child, Preschool , Female , Humans , Male , Middle Aged
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