ABSTRACT
BACKGROUND: Mycetoma is a chronic infection of cutaneous and subcutaneous tissue that can be caused by fungi or bacteria. It is endemic in tropical and subtropical areas but rare in Tunisia. PURPOSE: The purpose of this report is to describe epidemioclinical features, treatment and outcomes in patients presenting mycetoma in Tunisia. PATIENTS AND METHODS: The files of all patients treated for mycetoma in the Dermatology Department of La Rabta Hospital in Tunisia from 1982 to 2006 were retrospectively reviewed. RESULTS: A total of 15 cases of mycetoma were recorded during the study period. There were 6 men and 9 women with a mean age of 53.2 years. The most common clinical presentation was infiltrated erythematous plaques with sinus tracts (fistulas). Lesions were located on the foot in 12 cases. Thirteen patients reported the presence of grains in fluid discharging from fistulas. The cause of mycetoma was actinomycetes, i.e., Actinomadura madurae, in 9 cases and fungus in 6 cases including 3 due to Madurella mycetomi and 2 to Pseudallesheria boydii. Treatment was based on oral antibiotics for actinomycetoma and oral antifungals for eumycetoma. CONCLUSIONS: Mycetoma in Tunisia is still uncommon with a slight female predominance. The foot is the most frequent location. Diagnosis can be accomplished by direct mycologic examination, culture, and histololgy. There is no consensus on treatment that is often prolonged with numerous relapses.
Subject(s)
Actinobacteria/isolation & purification , Mycetoma/diagnosis , Mycetoma/epidemiology , Adult , Aged , Anti-Bacterial Agents/therapeutic use , Antifungal Agents/therapeutic use , Drug Therapy, Combination , Female , Humans , Male , Middle Aged , Mycetoma/drug therapy , Mycetoma/microbiology , Prevalence , Retrospective Studies , Risk Factors , Skin Diseases, Bacterial/diagnosis , Skin Diseases, Bacterial/epidemiology , Treatment Outcome , Tunisia/epidemiologyABSTRACT
The purpose of this report is to describe a case involving Kaposi sarcoma as the inaugural manifestation of HIV infection at the full-blown AIDS stage. The patient was a 59-year-old Tunisian man who presented with profuse subcutaneous nodules and multiple lymph nodes. Treatment was based on antiretroviral therapy in association with radiotherapy.
Subject(s)
Acquired Immunodeficiency Syndrome/diagnosis , Sarcoma, Kaposi/etiology , Humans , Male , Middle Aged , Sarcoma, Kaposi/pathology , Skin Neoplasms/etiology , Skin Neoplasms/pathology , Tongue Neoplasms/etiology , Tongue Neoplasms/pathologyABSTRACT
INTRODUCTION: Staphylococcus skin infections (SSI) are common. The emergence methicillin-resistant Staphylococcus aureus (MRSA) is a growing concern. AIM: To describe the epidemiological, clinical and bacteriological features of SSI in a hospital department. PATIENTS AND METHODS: This was a prospective study performed in the Dermatology and Bacteriology Department of the La Rabta Hospital during a period of three months (February-April 2008). Were included all cases presenting with a primary SSI. For each patient wee collected epidemiological, clinical, bacteriological and therapeutic features. RESULTS: Twenty-five patients were included in the study concerning 15 men and 10 women, with a mean age of 47 years. Clinical exam revealed a unique lesion in 52% of cases. The abscess was the predominant clinical form (40%). The bacteriological study isolated a Staphylococcus aureus in the lesion in 40 % of cases and in the other sites of staphylococcus portage in 24% of cases. 32 % of patients had MRSA. CONCLUSION: Dermatologists are increasingly faced with cutaneous infections caused by MRSA. Bacterial samples should be taken routinely and probabilistic antibiotic therapy for MRSA instituted in severe infections.
