ABSTRACT
The segregation analysis is made of inheritance of the E factor of the Cattell's 16PF Questionnaire on the basis of a population sample consisting of 108 free-structured pedigrees. The possibility of major gene control of inheritance for this quantitative trait is confirmed.
Subject(s)
Cattell Personality Factor Questionnaire , Genes , Genetics, Behavioral , Personality Inventory , Adolescent , Adult , Aged , Aging/genetics , Female , Genetics, Population , Genotype , Humans , Male , Middle Aged , Pedigree , Personality , PhenotypeABSTRACT
Within outbred Wistar stock, the pendulum movements are found to be inherited in what may be considered as a dominant mono- or oligogenic mode of inheritance with incomplete penetrance. This indicates that the albinism only permits the manifestation of the pendulum movements, which are also controlled by some other gene or genes. The pendulum movements show a positive genetic relation to catalepsy, although this relation is not strong: the proportion of animals with pendulum movements is 23% in the control population and 32% in F12-F16 bred for catalepsy (p less than 0.05). Within the latter, the proportion of animals with pendulum movements was 43% in the progeny of parents with phenotypically expressed catalepsy, and 29% in the progeny of phenotypically "normal" animals (p less than 0.01). The frequency of audiogenic seizures was 32% in the control population and 17% in F8-F16 bred for catalepsy (p less than 0.001). A genetic model is proposed to account for the paradoxical situation, where pendulum movements have a positive genetic relation both to catalepsy and audiogenic epilepsy, the catalepsy being at the same time negatively related to epilepsy.
