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Bull Exp Biol Med ; 148(4): 606-8, 2009 Oct.
Article in English | MEDLINE | ID: mdl-20396751

ABSTRACT

Specific binding of (3)H-flunitrazepam with synaptosomal membranes after exposure to open field test and "contact with predator" test was measured in C57Bl/6 and BALB/c mice. Stress-induced decrease in benzodiazepine binding after open field test was observed only in BALB/c mice and after contact with predator in both animal strains.


Subject(s)
Anti-Anxiety Agents/metabolism , Benzodiazepines/metabolism , Flunitrazepam/metabolism , Mice, Inbred BALB C , Mice, Inbred C57BL , Stress, Psychological , Animals , Anxiety , Behavior, Animal/physiology , Cats , Fear , Female , Male , Mice , Radioligand Assay , Synaptosomes/metabolism , Synaptosomes/ultrastructure
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