ABSTRACT
The authors' findings suggest that the clinical pattern of tuberculosis morbidity in adults and children has recently become worse. Severe caseous pneumonia with its acute onset and malignant course by the type of galloping consumption with massive bacterial isolation and deaths in 42.8% of cases was analyzed. The complicated course mainly of the primary tuberculosis complex (40.8%) and tuberculosis of the intrathoracic lymph nodes was seen in 25% of ill children. Tuberculous meningitis was diagnosed in 20% of cases in the morbidity pattern of extrapulmonary tuberculosis. The reasons for late detection of disease are the poor organization of prophylactic fluorographic examinations of the adult population, tuberculin diagnosis, vaccination, revaccination of BCG and chemoprophylaxis in children at risk. The authors note unawareness of tuberculosis among the adult population, which was found through questionnaires.
Subject(s)
Mass Screening/methods , Tuberculosis/diagnostic imaging , Tuberculosis/etiology , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Middle Aged , Morbidity , Quality of Life , Radiography , Retrospective Studies , Risk Factors , Surveys and Questionnaires , Survival Rate , Tuberculosis/epidemiologyABSTRACT
Circulating antituberculous antibodies in the sera from 89 patients with pulmonary tuberculosis and 11 patients with tumors and nonspecific inflammation in the lungs were evaluated using indirect hemagglutination and enzyme immunoassay. Specific antibodies were detected in 81.6 and 30% of tuberculous and nontuberculous patients, respectively.
Subject(s)
Tuberculosis, Pulmonary/diagnosis , Adult , Antibodies, Bacterial/blood , Antibody Specificity , Diagnosis, Differential , Female , Hemagglutination Tests , Humans , Immunoenzyme Techniques , Male , Middle Aged , Mycobacterium tuberculosis/immunology , Sensitivity and SpecificityABSTRACT
Clinical manifestations of tuberculosis in children and adolescents living in the Tumen region during 1984-1989 are analysed. Out of 432 of the patients, local forms of tuberculous infection were detected in 79.4% and pneumonia in 4.4% of the cases, while all the rest children proved to be just infected. The most prevailing among the pulmonary forms of the disease was intrathoracic lymphatic tuberculosis (52.3%) and among the non-pulmonary ones--tuberculous meningitis (3.5%). A complicated course of a tuberculous process was registered in 37.3% of the cases, especially in 2/3 of the patients with intrathoracic lymphatic tuberculosis (mainly of a bronchial type) as a consequence, in a number of cases, of the absence of BCG vaccination and the presence of tuberculous contact. Bronchoscopy undertaken in 244 children and adolescents made it possible to discover active changes in the bronchial mucosa in the first 1-2 months of therapy.
