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1.
ISA Trans ; 49(3): 348-57, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20347083

ABSTRACT

The study investigates a novel fuzzy feedback linearization strategy for control. The main contributions of this study are to construct a control strategy such that the resulting closed-loop system is valid for any initial condition with almost disturbance decoupling performance, and develop the feedback linearization design for some class of nonlinear control systems. The feedback linearization control guarantees the almost disturbance decoupling performance and the uniform ultimate bounded stability of the tracking error system. Once the tracking errors are driven to touch the global final attractor with the desired radius, the fuzzy logic control is immediately applied via a human expert's knowledge to improve the convergence rate. One example, which cannot be solved by the first paper on the almost disturbance decoupling problem, is proposed in this paper to exploit the fact that the almost disturbance decoupling and the convergence rate performances are easily achieved by the proposed approach.


Subject(s)
Fuzzy Logic , Industry/methods , Algorithms , Feedback , Kinetics , Linear Models , Mechanics , Physics
2.
Vaccine ; 23(48-49): 5563-71, 2005 Dec 01.
Article in English | MEDLINE | ID: mdl-16125286

ABSTRACT

Previously, we showed that murine prothymosin alpha (ProT) enhances the efficacy of a pseudorabies DNA vaccine delivered by bacterial vectors. In this study, we cloned and sequenced the cDNA for porcine ProT. The deduced amino acid sequence of porcine ProT exhibited high homology to ProT from other mammals. Oral Salmonella choleraesuis vaccine carrying the ProT eukaryotic expression plasmid protected mice against virulent S. choleraesuis challenge. The adjuvant effect of ProT on humoral and cellular immune responses enhanced protective efficacy of the vaccine. Furthermore, both humoral and cellular immune responses played roles in the protective immune responses induced by the vaccine. Collectively, our results show that delivery of the ProT gene carried by attenuated S. choleraesuis augmented the immunogenicity of oral S. choleraesuis vaccine.


Subject(s)
Antibody Formation/drug effects , Bacterial Vaccines/immunology , Protein Precursors/administration & dosage , Salmonella/immunology , Thymosin/analogs & derivatives , Vaccines, DNA/administration & dosage , Adjuvants, Immunologic/administration & dosage , Adjuvants, Immunologic/genetics , Administration, Oral , Animals , Antibodies, Bacterial/biosynthesis , Antibodies, Viral/biosynthesis , Bacterial Vaccines/administration & dosage , Bacterial Vaccines/genetics , Immunity, Cellular/drug effects , Mice , Protein Precursors/genetics , Salmonella/genetics , Salmonella Infections/immunology , Salmonella Infections/microbiology , Salmonella Infections/pathology , Salmonella Infections/prevention & control , Swine , Thymosin/administration & dosage , Thymosin/genetics , Vaccines, DNA/genetics
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