How do R&D and remittances affect economic growth? Evidence from middle-income countries.

Sustainable development through technical progress for middle-income countries (MICs) is overlooked in growth allied studies. Despite their crucial role in alleviating poverty and resource shortages, MICs encounter challenges in global economic competition, driving persistent efforts to find practical solutions. Therefore, this study explores the integrated impact of R&D expenditure and remittances on economic growth in MICs. Using data from 25 MICs between 1996 and 2021, this study employs the "2nd generation unit root" and "panel autoregressive distributed lag (ARDL)" methods. The "feasible generalized least square (FGLS)" techniques and the "Dumitrescu-Hurlin (D-H)" causality test are employed to verify the robustness of the panel ARDL estimation. The Westerlund cointegration tests confirm a long-term cointegration between variables. The findings of the panel ARDL approach show that R&D expenditure and remittances positively and significantly influence economic growth. The robustness of the panel ARDL results is confirmed by the FGLS estimation, which produces similar outcomes. The outcomes from the FGLS and the ARDL methods are additionally validated by the D-H causality check. Therefore, encouraging R&D and remittances is crucial to accelerate middle-income nations' economic growth. The study reveals a novel mechanism of R&D expenditures, remittances, and economic growth in MICs, shaping their mutual influence on this economic landscape. The study supports middle-income countries' policymakers in creating effective policies for their financial institutions regarding R&D expenditure and remittances.

impHFrEF trial: study protocol for an open-label, multicentre study of improvement the outcome of patients with heart failure in China using a mobile hEalth-supported platForm.

BACKGROUND: Patients with chronic heart failure (CHF) often have a long duration of illness, difficulty in attending follow-up visits, and poor adherence to treatment. As a result, they frequently cannot receive guideline-directed medical therapy (GDMT) at the desired or maximum tolerable drug dosage. This leads to high hospitalisation and mortality rates for HF patients. Therefore, effective management and monitoring of patients with HF to ensure they receive GDMT is crucial for improving the prognosis. DESIGN AND METHODS: This is a multicentre, open-label, randomised, parallel-group study involving patients with CHF across five centres. The study aims to assess the impact of an optimised GDMT model for HF patients, established on a mobile health (mHealth) platform, compared with a control group. Patients must have a left ventricular ejection fraction of less than 50% and be receiving medication titration therapy that has not yet reached the target dose, with a modest increase in N-terminal pro-B-type natriuretic peptide level. The primary composite outcome is worsening HF events (hospitalisation or emergency treatment with intravenous fluids) or cardiovascular death. ETHICS AND DISSEMINATION: On 22 December 2021, this study received ethical approval from the Ethics Review Board of the First Affiliated Hospital of Nanjing Medical University, with the ethics number 2021-SR-530. All study participants will be informed of the research purpose and their participation will be voluntary. Informed consent will be obtained by providing and signing an informed consent form. We will ensure compliance with relevant laws and regulations regarding privacy and data protection. The results of this study will be published in a peer-reviewed academic journal. We will ensure that the dissemination of study results is accurate, clear and timely. TRIAL REGISTRATION NUMBER: ChiCTR2200056527.

How does the digital service trade nonlinearly affect carbon emissions? Empirical evidence from G20 countries.

This study explores the nonlinear relationship between digital service trade and carbon emissions using the data of 42 G20 countries from 2005 to 2021. It is concluded that this relationship appears to be an inverted U-shape. When the digital service trade is inadequate, this exacerbates carbon emissions. Only when the digital service trade is above this point does it become beneficial to environmentally sustainable development. Mediation analyses indicate that the digital service trade increases carbon emissions by increasing emissions from digital infrastructure and decreases them by optimizing the industrial structure and adopting low-carbon technologies. Furthermore, the nonlinear association is moderated by human capital. When human capital is insufficient, it is harder for the digital service trade to curb carbon emissions. Accordingly, this study is helpful to develop the digital service trade and achieving the goals of carbon peak and neutralization and the sustainable growth of the environment.

The asymmetric impact of renewable energy consumption on the economic growth of emerging South and East Asian countries: A NARDL approach.

The question of economic development is so essential that specialists, international leaders, and every government are continually working on how to tackle this problem. Renewable energy is a means to save planet's ecology and foster long-term economic viability. This study explores the asymmetric effect of renewable energy consumption (RE) on emerging South and East Asian countries' economic growth by the non-linear autoregressive distributed lag (NARDL) approach. Also, it employs the generalized least square (GLS) method and panel causality test to grasp this impact. The GLS assessment exposes that positive and negative (P&S) mechanisms of RE positively influencing GDP while urbanization has an adverse influence. The PMG approach also delivers equivalent outcomes and authenticates the robustness of GLS results. The causality results provide relations between GDP and other variables. There is a conservation mechanism between the negative shock of RE consumption and GDP, while the positive shock of RE to GDP is observed from the feedback mechanism. We observed different interactions of CO2, P&S shocks of RE, and non-renewable consumption on GDP. These findings support policymakers of South and East Asian countries in formulating effective rules for their financial institutions regarding energy guidelines. In addition, considering P&S shocks from RE specifies that effective outcomes can be attained in economic growth while formulating energy guidelines.

Investigating the associations of consumer financial knowledge and financial behaviors of credit card use.

The growing economic uncertainty makes consumers realize the importance of financial preparedness and management ability. Based on the U.S. National Financial Capability Study dataset from 2009, 2012, 2015, and 2018, this study explores the nexus between consumer financial knowledge and financial behaviors of credit card use. The results indicate that financial knowledge positively affects consumer credit card ownership and desirable financial behaviors of credit card use, and is negatively related to undesirable credit card behaviors. The results are robust to different regression methods and after removing income outliers. The heterogeneity test shows that financial knowledge cannot enhance desirable credit card behaviors because of the income limitations in the low-income group. Therefore, there are implications for policymakers, financial sectors, and consumers to improve consumers' usage of credit cards and cultivate proper consumption habits by enhancing consumer financial knowledge.

Informal financial education and consumer financial capability: The mediating role of financial knowledge.

With the development of the economy, family wealth continues to accumulate, and more and more consumers participate in financial management affairs. As an important way to improve financial knowledge, informal financial education is vital to consumer financial capability. Utilizing data from the 2012, 2015, and 2018 US National Financial Capability Study and the approaches of ordinary least squares and ordered probit regression are employed to produce more accurate estimates. Meanwhile, the study also explores the mediating effects of financial knowledge between informal financial education and consumer financial capability. The results show that informal financial education has a positive effect on the improvement of consumer financial capability. Besides, financial knowledge partially mediates the nexus between informal financial education and consumer financial capability. Therefore, policymakers are encouraged to formulate measures to promote financial education programs not only in schools and universities but also in workplaces or communities. Companies also should offer more opportunities for their employees to receive financial education and further enhance their financial capability. Consumers should be aware of the importance of financial education and actively learn financial knowledge to improve financial capability and further enhance financial satisfaction.

Inhibition Effects of Nippostrongylus brasiliensis and Its Derivatives against Atherosclerosis in ApoE-/- Mice through Anti-Inflammatory Response.

Atherosclerosis (AS) is a dominant and growing cause of death and disability worldwide that involves inflammation from its inception to the emergence of complications. Studies have demonstrated that intervention with helminth infections or derived products could modulate the host immune response and effectively prevent or mitigate the onset and progression of inflammation-related diseases. Therefore, to understand the molecular mechanisms underlying the development of atherosclerosis, we intervened in ApoE-/- mice maintained on a high-fat diet with Nippostrongylus brasiliensis (N. brasiliensis) infection and immunized with its derived products. We found that N. brasiliensis infection and its derived proteins had suitable protective effects both in the initial and progressive stages of atherosclerosis, effectively reducing aortic arch plaque areas and liver lipid contents and downregulating serum LDL levels, which may be associated with the significant upregulation of serum anti-inflammatory cytokines (IL-10 and IL-4) and the down-regulation of proinflammatory cytokines (TNF-α and IFN-γ) in the serum. In conclusion, these data highlighted the effective regulatory role of N. brasiliensis and its derived proteins in the development and progression of atherosclerosis. This could provide a promising new avenue for the prevention and treatment of atherosclerosis.