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Sci Rep ; 11(1): 15709, 2021 08 03.
Article in English | MEDLINE | ID: mdl-34344965

ABSTRACT

Calcaneal quantitative ultrasonography (QUS) is a useful prescreening tool for osteoporosis, while the dual-energy X-ray absorptiometry (DXA) is the mainstream in clinical practice. We evaluated the correlation between QUS and DXA in a Taiwanese population. A total of 772 patients were enrolled and demographic data were recorded with the QUS and DXA T-score over the hip and spine. The correlation coefficient of QUS with the DXA-hip was 0.171. For DXA-spine, it was 0.135 overall, 0.237 in females, and 0.255 in males. The logistic regression model using DXA-spine as a dependent variable was established, and the classification table showed 66.2% accuracy. A receiver operating characteristic (ROC) analyses with Youden's Index revealed the optimal cut-off point of QUS for predicting osteoporosis to be 2.72. This study showed a meaningful correlation between QUS and DXA in a Taiwanese population. Thus, it is important to pre-screen for osteoporosis with calcaneus QUS.


Subject(s)
Absorptiometry, Photon/methods , Bone Density , Calcaneus/diagnostic imaging , Osteoporosis/diagnostic imaging , Ultrasonography/methods , Aged , Aged, 80 and over , Female , Humans , Logistic Models , Male , Mass Screening , Middle Aged , Prognosis , ROC Curve , Sensitivity and Specificity , Taiwan
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