Subject(s)
Cross Infection , Disease Outbreaks , Measles virus , Measles , Adult , Child , Child, Preschool , China , Cross Infection/epidemiology , Cross Infection/transmission , Cross Infection/virology , Female , Health Personnel , Humans , Infant , Male , Measles/epidemiology , Measles/transmission , Measles/virology , Measles virus/classification , Measles virus/genetics , Measles virus/isolation & purification , Taiwan/epidemiology , TravelSubject(s)
Breast/pathology , Paget's Disease, Mammary/pathology , Aged , Biopsy , Breast Neoplasms/diagnostic imaging , Breast Neoplasms/pathology , Epidermis/pathology , Female , Humans , Immunohistochemistry , Paget's Disease, Mammary/diagnostic imaging , Pigmentation , Radiography , UltrasonographyABSTRACT
Angioma serpiginosum is an uncommon, acquired vascular nevoid disorder with capillary dilation and proliferation in the papillary dermis. The eruptions are asymptomatic and characterized by grouped, erythematous to violaceous, serpiginous and punctate macules. The condition usually appears in females during adolescence on unilateral lower extremities and the buttocks. We report a rare case with a late onset and atypical distribution of lesions in a 48-year-old female patient who had groups of punctate lesions on her left foot for four to five years. Histopathological examination showed hyperkeratosis and multiple dilated and proliferated capillaries in the papillary dermis. Inflammation and extravasation of red blood cells were not found. According to the clinical and pathological findings, we established a diagnosis of angioma serpiginosum. She was treated with a pulsed dye laser, and the angiomatous lesions subsequently improved.
Subject(s)
Skin Diseases, Vascular/diagnosis , Telangiectasis/diagnosis , Dermatologic Surgical Procedures , Female , Foot Diseases/diagnosis , Foot Diseases/surgery , Humans , Lasers, Dye/therapeutic use , Middle Aged , Skin/blood supply , Skin/pathology , Skin Diseases, Vascular/surgery , Telangiectasis/surgery , Treatment OutcomeABSTRACT
An echovirus 11 outbreak occurred among neonates in an obstetric clinic in November 2003. Thirteen neonates were transferred to our medical center, and all were found to have echovirus 11 infection. Viral studies were performed for 32 other infants born in the clinic during the same period, including 30 asymptomatic neonates and 2 febrile infants transferred to another hospital. Two of the asymptomatic infants had echovirus 11 isolated from rectal swabs. The first patient transferred to our medical center developed extensive hemorrhage and died 6 days later. Three family members of this infant were also proved to have echovirus 11 infections. One other infant had a fulminant course and had residual hepatic impairment. The other infants had no complications. Viral studies in the 24 nursery staff were all negative. This outbreak shows how a neonatal enterovirus outbreak can occur in a nursery, starting from an infected infant in the incubation period. Early recognition and prompt management of an outbreak is important to prevent further spread of the infection.
