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2.
Cureus ; 16(4): e57699, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38711700

ABSTRACT

Palatal solitary neurofibromas (SNFs), not linked to neurofibromatosis type 1, are uncommon. A 45-year-old female with a palatal SNF underwent non-surgical treatment using liquid nitrogen cryotherapy (LNC). The lesion, initially 9 x 8 x 3 mm, was treated with two 1-2 minute freeze-thaw cycles, progressively extended to two 2-2 minute freeze-thaw cycles to address the refractoriness. After four LNC sessions, the lesion resolved without recurrence at five months. This case demonstrates LNC's efficacy as a surgical alternative for palatal SNF, offering a non-invasive option for patients declining surgery. The positive outcome warrants further research into LNC's role in managing similar benign lesions.

3.
J Plast Reconstr Aesthet Surg ; 92: 26-32, 2024 May.
Article in English | MEDLINE | ID: mdl-38489984

ABSTRACT

BACKGROUND: Oral submucous fibrosis is a global health concern associated with betel quid use and results in trismus, which can be either primary or secondary in origin. Severe cases often require trismus release with free-flap reconstruction. This study examined longitudinal outcome trends following trismus release and compared the outcomes of patients with primary and secondary oral submucous fibrosis-related trismus. METHODS: We conducted a retrospective cohort study by including patients who underwent trismus release between 2013 and 2022. All procedures were performed by a single surgical team to ensure technique standardisation. We measured the maximum mouth opening, the interincisal distance, perioperatively and 1, 2, 3, 4, 6 and 12 months post-operatively. Data were analysed using generalised estimating equations. RESULTS: A total of 35 patients were included in the study, 17 with primary and 18 with secondary oral submucous fibrosis-related trismus. Initially, patients with primary oral submucous fibrosis-related trismus had greater interincisal distance gains than those with secondary oral submucous fibrosis-related trismus (p = 0.015 and p = 0.025 at 3 and 4 months post-operatively, respectively). However, after 12 months, this initial advantage faded, with comparable interincisal distance improvements in patients with primary and secondary disease, despite the more complex surgical procedures required in secondary cases. CONCLUSION: Surgeons should carefully consider the benefits of trismus release procedures for patients with secondary oral submucous fibrosis-related trismus by recognising the changes in post-operative outcomes.


Subject(s)
Free Tissue Flaps , Oral Submucous Fibrosis , Trismus , Humans , Trismus/etiology , Oral Submucous Fibrosis/surgery , Oral Submucous Fibrosis/complications , Male , Female , Retrospective Studies , Adult , Free Tissue Flaps/adverse effects , Middle Aged , Plastic Surgery Procedures/methods , Plastic Surgery Procedures/adverse effects , Longitudinal Studies , Treatment Outcome
7.
J Surg Oncol ; 127(6): 929-936, 2023 May.
Article in English | MEDLINE | ID: mdl-36806041

ABSTRACT

INTRODUCTION: Trismus after oral cancer is frequent, with scarce evidence of surgical release treatment in these patients. OBJECTIVES: The objective of this study is to determine the results of trismus release and free flap reconstruction after oral cancer treatment, establish immediate and long-term results, and detect factors that influence outcome. MATERIALS AND METHODS: A retrospective study was performed. Preoperative, intraoperative, and follow-up interincisal distances were measured. The intraoperative, long-term gain, and postoperative loss were calculated. Analysis of the long-term results with the preoperative and intraoperative variables was performed. RESULTS: Surgical release immediately increased the interincisal distance by 29.25 mm. Sixty-six percent of this gain was lost due to trismus recurrence, giving a long-term interincisal gain of 9.90 mm. Worse results were observed in patients with previous high-stage tumors, maxillectomies, skin resections, and previous radiotherapy. The were no significant differences in the results depending on the type of release or reconstruction performed, with the exception of the reconstruction with the sural flap, which presented worse results. Patients with trismus of ≤10 mm could have more range for improvement after this surgery. CONCLUSIONS: The results of this surgery are moderate in the long term due to high trismus recurrence in spite of aggressive treatment.


Subject(s)
Mouth Neoplasms , Plastic Surgery Procedures , Humans , Trismus/surgery , Retrospective Studies , Mouth Neoplasms/pathology , Surgical Flaps/surgery , Treatment Outcome
8.
Plast Reconstr Surg ; 150(4): 863e-868e, 2022 10 01.
Article in English | MEDLINE | ID: mdl-35939649

ABSTRACT

SUMMARY: Dental implant complications in patients with a symphysis cross-arch defect occur following fibula mandible reconstruction due to mechanical stress. The authors compared implant outcomes after single-barrel fibula mandible reconstruction with immediate implant placement or after completion of vertical distraction osteogenesis.


Subject(s)
Dental Implants , Mandibular Neoplasms , Osteogenesis, Distraction , Bone Transplantation , Dental Implantation, Endosseous , Fibula/surgery , Humans , Mandible/surgery , Mandibular Neoplasms/surgery
9.
J Surg Oncol ; 117(2): 142-149, 2018 Feb.
Article in English | MEDLINE | ID: mdl-28833146

ABSTRACT

BACKGROUND AND OBJECTIVES: This study aims to review our experience in trismus release followed by free flap reconstruction after radiotherapy in oral and oropharyngeal cancer, describe the results obtained in long-term follow-up and identify possible predictors of outcome. METHODS: Patients' demographics, tumor characteristics and treatment where retrieved. Surgical release and reconstructive procedures were detailed. Interincisor distances (IIDs) where measured preoperatively (PO-IID), intraoperatively after release (IO-IID) and in the last follow-up (FU-IID). Potential predictors of outcome in terms of interincisor long-term gain (LT-gain) and postoperative loss (PO-loss) were analyzed. RESULTS: Twenty-eight patients were included in our study. The mean LT-gain was 8.9 ± 7.0 mm, and the PO-loss was 22.14 ± 7.27 mm. Patients with a PO-IID of 10 mm or less had a significant higher LT-gain (P = 0.038). Predictors of worse outcome included having received a previous maxillectomy during tumor ablation (lower LT-gain, P = 0.035), and previous buccal mucosa resection (higher PO-loss, P = 0.044). CONCLUSIONS: Trismus release and free flap reconstruction after radiotherapy in oral and oropharyngeal cancer patients seems to be associated with modest long term results and a high incidence of trismus recurrence, particularly in cases of prior buccal resections or maxillectomy. Patients should be adequately informed and carefully selected before indicating the procedure.


Subject(s)
Carcinoma, Squamous Cell/radiotherapy , Free Tissue Flaps , Mouth Neoplasms/radiotherapy , Oropharyngeal Neoplasms/radiotherapy , Plastic Surgery Procedures , Radiotherapy/adverse effects , Trismus/surgery , Adult , Carcinoma, Squamous Cell/complications , Carcinoma, Squamous Cell/pathology , Female , Follow-Up Studies , Humans , Male , Middle Aged , Mouth Neoplasms/complications , Mouth Neoplasms/pathology , Oropharyngeal Neoplasms/complications , Oropharyngeal Neoplasms/pathology , Prognosis , Retrospective Studies , Trismus/etiology , Trismus/pathology
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