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1.
Chin J Integr Med ; 24(12): 950-955, 2018 Dec.
Article in English | MEDLINE | ID: mdl-30178090

ABSTRACT

Angiogenesis in atherosclerotic plaque plays a critical role in the mechanism of atherosclerotic physiopathology. Present consensus shows that angiogenesis in atherosclerotic plaque is mainly resulted in hypoxia, inflammation and some pro-angiogenic factors. The homeostasis in plaque, which is hypoxic and infiltrated by inflammatory cells, may lead to angiogenesis, increase the plaque instability and the incidence rate of vascular events. This article reviews the progression of pathogenetic mechanism, physiopathological significance, relevant detecting technique and corresponding therapeutic methods of Chinese and Western medicine of angiogenesis in atherosclerotic plaque, so as to provide more theoretical basis for atherosclerotic clinical treatment.


Subject(s)
Biomedical Research , Neovascularization, Pathologic/therapy , Plaque, Atherosclerotic/pathology , Animals , Humans , Medicine, Chinese Traditional
2.
J Zhejiang Univ Sci B ; 18(5): 449-452, 2017 May.
Article in English | MEDLINE | ID: mdl-28471119

ABSTRACT

Pheochromocytoma is a rare neuroendocrine tumor which derives from chromaffin cells of the adrenal gland or relevant to sympathetic nerves and ganglia. The clinical features of pheochromocytoma are various. Paroxysmal episodes of serious hypertension, headache, palpitation, and diaphoresis are the typical manifestations (Bravo, 2004). Hypotension shock, pulmonary edema, and acute coronary syndrome induced by pheochromocytoma are uncommon (Malindretos et al., 2008; Batisse-Lignier et al., 2015). In this study, we present a rare case of cystic pheochromocytoma causing recurrent hypotension shock, non-cardiogenic pulmonary edema, and acute coronary syndrome, and the possible mechanisms are discussed.


Subject(s)
Adrenal Gland Neoplasms/complications , Adrenal Gland Neoplasms/diagnosis , Pheochromocytoma/complications , Pheochromocytoma/diagnosis , Pulmonary Edema/diagnosis , Pulmonary Edema/etiology , Shock/etiology , Adrenal Gland Neoplasms/therapy , Cysts/complications , Cysts/diagnosis , Cysts/therapy , Diagnosis, Differential , Female , Humans , Hypotension/diagnosis , Hypotension/etiology , Hypotension/therapy , Middle Aged , Pheochromocytoma/therapy , Pulmonary Edema/therapy , Recovery of Function , Recurrence , Shock/diagnosis , Shock/prevention & control , Treatment Outcome
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