High-Performance Multi-Level Inverter with Symmetry and Simplification.

This paper presents a high-performance, multilevel inverter with symmetry and simplification. This inverter is a single-phase, seven-level symmetric switched-capacitor inverter based on the concept of the double voltage clamping circuit connected to the half-bridge circuit. Above all, only a single DC power supply is used to achieve a single-phase inverter with seven levels and a voltage gain of three. In addition to analyzing the operating principle of the proposed switched-capacitor multilevel inverter in detail, the stability analysis and controller design are carried out by the state-space averaging method. The feasibility and effectiveness of the proposed structure are validated by some simulated results based on the PSIM simulation tool and by some experiments using FPGA as a control kernel, respectively. However, in this study, the switches were implemented by MOSFETs to meet a high switching frequency. These MOSFETs can be replaced by IGBTs in the motor drive applications so that the used switching frequency can be reduced.

[Regulative Role For Noncoding RNAs During Skeletal Muscle Development and Disease].

Noncoding RNAs, including long noncoding RNAs (IncRNAs) and microRNAs (miRNAs), are close to myogenesis, regulating of muscle fiber type and muscle diseases. Recently, circulating ncRNAs have become research focus for they could as potential biomarkers for the screening and early diagnosis of some diseases. We are confident that the role of nccoding RNAs during skeletal muscle development will bring potential target for treatment of muscle diseases in the future.

High myopia as a risk factor in primary open angle glaucoma.

Glaucoma, one of the leading causes of irreversible blindness in the adult population worldwide, is a progressive optic neuropathy. Primary open angle glaucoma (POAG) is the most commonly reported type of glaucoma in population based prevalence studies worldwide. Elevated intraocular pressure is a well-known major risk factor for POAG. In addition, there is growing evidence that other risk factors like age, gender, race, refractive error, heredity and systemic factors may play a role in glaucoma pathogenesis. Many studies found that high myopia has been associated with POAG, however, direct and convincing evidences are still lacking. The aim of this review is to summarize the evidences implicating high myopia as a risk factor in the pathogenesis of POAG.