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1.
J Am Med Dir Assoc ; 21(9): 1346-1348, 2020 09.
Article in English | MEDLINE | ID: mdl-32723534

ABSTRACT

In recent years, subacute care units (SCUs) have emerged as alternatives to acute hospitalization for selected emergency department (ED) patients who might benefit from a short period of inpatient stay within a less acute setting. We developed a new protocol to directly admit selected older patients from our acute hospital's (AH) ED to the SCU of a partner community hospital, making use of our ED's short-stay ward as a transit area to overcome administrative, financial, and clinical barriers. The new protocol has removed the need for intervening stays of longer than 24 hours at our AH, reduced overall length of stay across both institutions, decreased hospital admissions, and reduced the number of patient hand-offs.


Subject(s)
Emergency Service, Hospital , Subacute Care , Hospitalization , Hospitals, Community , Humans , Length of Stay , Patient Admission
2.
Nat Commun ; 4: 1426, 2013.
Article in English | MEDLINE | ID: mdl-23385571

ABSTRACT

Chinese tree shrews (Tupaia belangeri chinensis) possess many features valuable in animals used as experimental models in biomedical research. Currently, there are numerous attempts to employ tree shrews as models for a variety of human disorders: depression, myopia, hepatitis B and C virus infections, and hepatocellular carcinoma, to name a few. Here we present a publicly available annotated genome sequence for the Chinese tree shrew. Phylogenomic analysis of the tree shrew and other mammalians highly support its close affinity to primates. By characterizing key factors and signalling pathways in nervous and immune systems, we demonstrate that tree shrews possess both shared common and unique features, and provide a genetic basis for the use of this animal as a potential model for biomedical research.


Subject(s)
Genome/genetics , Tupaia/genetics , Animals , China , Genetic Variation , Hepacivirus/physiology , Hepatitis C/genetics , Hepatitis C/virology , Humans , Immune System/metabolism , Inactivation, Metabolic/genetics , Mice , Nervous System/metabolism , Phylogeny , Sequence Analysis, DNA , Tupaia/immunology
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