ABSTRACT
UNLABELLED: The objective of this study was to evaluate the reliability and construct validity of the Chinese parent form (PF50) and child form (CF87) of the Child Health Questionnaire (CHQ). METHODS: To assess the construct validity and reliability of the Chinese versions, we invited 1099 parents of healthy children and 816 school children to complete the Chinese CHQ-PF50 and CHQ-CF87, respectively. RESULTS: Psychometric analysis on item convergent validity and discriminant validity showed > or = 99% rates of success for all 10 scales in the CF87 and > or = 94% for all but one scale in the PF50, the exception being general health scale (86%). We observed minimal floor effects for both questionnaires, but substantial ceiling effects for five scales in both the PF50 and CF87 (physical functioning, role-emotional/behavioral, role-physical, bodily pain and family activities). A substantially lower ceiling effect was observed for the physical scale and bodily pain in the CF87 (19% and 25%, respectively) relative to the PF50 (46% and 42%, respectively). The median alpha coefficient for CF87 and PF50 was 0.90 (range, 0.80-0.94) and 0.78 (range, 0.44-0.88), respectively. CONCLUSIONS: Our findings suggest that the Chinese CHQ-PF50 and CHQ-CF87 are robust and sufficiently reliable for group comparisons and perhaps also for use in other Chinese populations.
Subject(s)
Child Welfare , Health Status Indicators , Parents/psychology , Psychometrics/instrumentation , Quality of Life , Surveys and Questionnaires , Adolescent , Adult , Aged , Child , Child, Preschool , China , Feasibility Studies , Female , Humans , Male , Middle Aged , Pilot ProjectsABSTRACT
11,451 health persons were inoculated with live attenuated hepatitis A vaccine (H2 strain) in 3 batches. Among them, 785 were tested for anti-HAV antibody response by ELISA. The results showed that H2-strain vaccine got a quick antibody response (2-5 weeks) and a high seroconversion rate (92.9%). Also, the titers of antibodies to HAV ranged from 1:2 to 1:32. The seroconversion of the first 12 recipients lasted for 3 years. The primary epidemiological studies demonstrated that H2-strain vaccine was effective in preventing hepatitis A. The relation between the positive rate of antibody and different dosage showed that 10(6.5)TCID50 could get a highest seroconversion rate (100%).
