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Mol Cell ; 83(5): 657-659, 2023 03 02.
Article in English | MEDLINE | ID: mdl-36868188

ABSTRACT

Zhu and Hart1 use dual-specificity RNA aptamers to recruit cellular O-GlcNAc transferase (OGT) and induce O-GlcNAc on target proteins like ß-catenin, revealing that O-GlcNAc stabilizes ß-catenin and enhances its transcriptional activity.


Subject(s)
Aptamers, Nucleotide , N-Acetylglucosaminyltransferases , beta Catenin , N-Acetylglucosaminyltransferases/chemistry
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