ABSTRACT
@#AIM: To summarize and analyze the clinical data of patients with ocular injuries during Spring Festival in the past five years, and analyze the effect of injury on the patient and visual outcome.<p>METHODS: The clinical data of 155 cases of ocular trauma admitted during the Spring Festival from 2013 to 2017 were collected, including their age, sex, place, course, causes, nature of trauma, <i>etc</i>. The clinical features and the trends of ocular traumas in each year were summarized, and analysis the impact of injury on the vision prognosis, probe the relationship between ocular trauma sore and hospitalization days and costs. <p>RESULTS: A total of 155 ocular trauma patients(158 eyes)were enrolled in this study. The ratio of male to female was 6.05: 1, the mean age was 34.8±20.0 years old, and the proportion of 30-44 years old was higher. There were more rural residents than urban residents, showing differences on the course of injury(<i>Z</i>=-3.232, <i>P</i><0.01). The general trend was that the number of people injured in the Spring Festival holidays increased. Fireworks were the main cause of injury, accounting for 41.9%, followed by toy gun injuries(16.1%), and the latter was the main cause of child injury. Closed globe injury accounted for a large proportion(76.6%)). Conservative treatment were needed for 71 eyes(44.9%), the majority patients still for surgery intervention. Open globe injury of ocular trauma sore was lower than closed globe injury(<i>Z</i>=-5.249, <i>P</i><0.01), and the blindness rate of the former was higher. The visual acuity on discharge was significantly higher than admission(<i>Z</i>=-7.487, <i>P</i><0.01). Hospitalization expenses increased with the number of hospitalization days, and both were positively correlated(<i>r<sub>s</sub></i>=0.755, <i>P</i><0.01). The average ocular trauma sore was about 77.41±16.96, which was negatively correlated with hospitalization costs(<i>r<sub>s</sub></i>=-0.474, <i>P</i><0.01)and negative correlation with hospitalization days(<i>r<sub>s</sub></i>=-0.359, <i>P</i><0.01). <p>CONCLUSION: During the Spring Festival, ocular trauma occurred in middle-aged men and rural population. Fireworks were the main cause of injury. The eyeball shape and visual function was damaged after ocular trauma. Timely diagnosis and treatment could save the visual function of some patients. The heavier the injury, the higher the hospital days and hospitalization costs, which increased the personal and social burden.
ABSTRACT
Objective To explore the expression levels of serum nitric oxide(NO)and nitric oxide synthase(NOS) between Han and Uyghur nationality patients with anti-tuberculosis drug-induced liver injury(ATDLI). Methods Patients with confirmed ATDLI in Chest Hospital of Xinjiang Uyghur Autonomous Region and First Affiliated Hos-pital of the Medical College of Shihezi University between January 2015 and May 2016 were chosen and divided into Han group and Uyghur group.By detecting the expression levels of NO and NOS in serum of ATDLI patients,ex-pression levels of serum NO and NOS in ATDLI patients of different gender,body mass index(BMI),and liver function injury were compared.Results 100 ATDLI patients in Han group and 135 in Uyghur group were recruited in study. Expression levels of NO and TNOS in Han group were(134.24±27.60)μmol/L and(33.01 ±4.23)U/mL respectively,in Uyghur groups were(97.10±17.41)μmol/L and(27.41 ±3.95)U/mL respectively,serum levels of NO,TNOS,iNOS,and eNOS in Han patients were all higher than Uyghur patients,difference was statistically significant(P<0.01). In Han ATDLI group,serum levels of NO and TNOS in male patients were both higher than female patients(P<0.05);in Uyghur ATDLI group,serum levels of NO,TNOS,and iNOS in male patients were all higher than female patients(P<0.01). The expression levels of serum NO,TNOS,and iNOS of Han group were all higher than the same gender in Uyghur group(P<0.001),difference in levels of NO and TNOS among different body mass index(BMI)groups in Han and Uyghur patients were both statistically significant(P<0.01). In both group,levels of NO and TNOS in obese patients were both higher than lean patients and normal weight patients(P<0.05). The correlation analysis showed that NO levels of Han and Uyghur groups were both positively correlated with BMI(r=0.444,0.677,respectively,P<0.01). There were significant differences in serum NO and NOS levels between Han and Uyghur patients with different degrees of liver injury(P<0.05);NO and NOS levels in both groups with mild liver injury were both lower than those with moderate and severe injury (P<0.001).Conclusion Serum NO and NOS levels between ATDLI Han group and Uyghur group are different,serum NO level is related to BMI,and it can increase with the degree of liver injury.
ABSTRACT
The finite element method （FEM） is a numerical computation method based on computer technology, and has been gradually applied in the fields of medicine and biomechanics. The finite element analysis can be used to explore the loading process and injury mechanism of human body in traffic injury. FEM is also helpful for the forensic investigation in traffic injury. This paper reviews the development of the finite element models and analysis of brain, cervical spine, chest and abdomen, pelvis, limbs at home and aboard in traffic injury in recent years.
