Ecotoxicological Assessment of Potentially Toxic Elements (as, Cd, Ni and V) Contamination in the Sediments of Southern Part of Caspian Sea, the Case of Khazar Abad, Mazandaran Province, Iran.

In this study, the contamination of arsenic, cadmium, nickel and vanadium in the surface sediments of Khazar Abad, in the southern part of the Caspian Sea was analyzed in 2019 using ecotoxicological indices. The geoaccumulation index (Igeo) values showed that the sediment samples of the study area could be classified as 'unpolluted' to 'strongly polluted', while, the values of toxic units (TUs) with an average value of 0.591 indicated that all samples could be classified as 'at low toxicity level'. Moreover, the ecotoxic risk level (TRI) in the studied sediments was classified at the level of 'no toxic risk' for Cd and 'considerable toxic risk' for As and Ni. On the whole, the results showed that the levels of contamination were higher in the areas where industrial, domestic and agricultural wastewater was discharged (i.e. S4, S7, S10, S11 and S12). Finally, to avoid and/or reduce ecotoxicological dangers, periodic monitoring of PTEs in the coastal strip of the southern part of the Caspian Sea is recommended.

Impact of treatment with inhaled corticosteroids on bone mineral density of patients with asthma: related with age.

UNLABELLED: The effect of inhaled corticosteroid on bone mineral density (BMD) was investigated in 44 asthmatic patients after median treatment duration of 6.5 years. Compared with controls, BMD decreased only in patients aged <50 years in both the spine (11.3 %, p = 0.013) and hip (8.8 %, p = 0.044), whereas in patients ≥50 years BMD did not decrease significantly. INTRODUCTION: The results of studies which addressed the impact of inhaled corticosteroid (ICS) therapy on BMD of patients with asthma are conflicting. This case-control study aimed to compare BMD status in ICS user with asthma with healthy controls according to age. METHODS: BMD at the lumbar spine (LS), femoral neck (FN) was measured by dual energy X-ray absorptiometry (DEXA). Patients and controls were compared according to BMD gr/cm(2), BMD T-score, BMD Z-score, frequency of osteoporosis (defined as BMD T-score ≤-2.5), and frequency of patients with BMD Z-score <-1 at LS and FN with regard to age <50 and ≥50 years old. RESULTS: Forty-four ICS user patients (females 63.6 %) with median treatment duration of 6.5 years and 50 controls (females, 69.4 %) with respective mean age of 49.2 ± 9.5 and 47.4 ± 10.5 years (p = 0.38 and p = 0.35) entered the study. Overall LS-BMD and FN-BMD gr/cm2 in total patients were lower than in controls by 6 % (p = 0.065) and 5.9 % (p = 0.09), respectively. In patients <50 years, mean LS-BMD gr/cm(2) was lower than controls by 11.3 % (p = 0.013) and FN-BMD by 8.8 % (p = 0.044). Mean BMD T-score and BMD Z-score in both measurement sites were also lower than controls (p = 0.013 and 0.01, respectively. Frequency of osteoporosis did not differ but frequency of patients with BMD Z-score <-1 was significantly higher in patients (odds ratio (OR) = 6.57 95 % CI, 1.8-23.9, p = 0.004). In age group ≥50 years old, reduction of BMD in both measurement sites did not reach to a significant level. CONCLUSION: This study indicates that BMD reduction in ICS user with asthma is dependent on age and appears that younger patients are at greater risk of BMD loss. These findings suggest preventive measures particularly in patients <50 years.

Influencing factors on cervical cancer screening from the Kurdish women's perspective: A qualitative study.

Aim:This study was aimed to explore and describe the Kurdish women's perception of cervical cancer screening. Methods: A qualitative design based on a conventional content analysis approach. Purposive sampling was applied to 19 women chosen, who had a Pap smear or refused to have one. The study was performed in the Kurdistan Region, Iraq. Semi-structure din-depth individual interviews were carried out to collect data. Results: Four main themes including conflict, belief, and awareness about cervical cancer screening and socio-cultural factors emerged during data analysis Conclusions: Cervical cancer has a high mortality rate in the developing countries. However, only a few Kurdish women participated in the cervical cancer screening in the Kurdistan Region, Iraq. Understanding the factors associated with the women's perception of cervical cancer could guide future educational planning and clinical interventions improve the cervical cancer screening.

Relationship of sexual assault with self-concept and general health in victims referred to forensic Center in Ahvaz city.

AIM OF THE STUDY: We aimed to study the relationship of sexual assault with self-concept and the general health of the victims referred to forensics in Ahvaz city (Iran). MATERIAL AND METHODS: It was a cross-sectional descriptive and analytical study that was designed by two groups as case and control which has done on 128 subjects. Sixty-four rape victims who were referred to the forensic center, considered as case group and in control group, 64 people who were being referred to health clinics in Ahvaz city. The data were collected through Rogers's standard self-concept and general health questionnaires. Questionnaires were filled in self-completion way. Data had entered and analyzed by using SPSS software (version 22). A level of significance was less than 0.05. RESULTS: The average score of self-concept in the case group was 14.97 ±4.78 and in control group was 6.08 ±2.9. Average score of general health of the case and control groups, respectively, were 51.09 ±18.07 and 16.92 ±12.79. A significant statistical difference between the average score of self-concept, social functioning, physical and general health components in the groups was observed. CONCLUSIONS: More negative self-concept and vulnerable general health was observed in the rape victims group than in the control group. Providing counseling and health services and family and social support of these victims can be effective in their general health promotion.

Common cancers in Khuzestan province, south west of Iran, during 2005-2011.

UNLABELLED: Cancer is the third highest cause of premature mortality in Iran. We aimed to determine trend of common cancers in Khuzestan province, Iran. METHODS: It was a hospital based survey on 4065 subjects from their hospital files, those had registered as cancer case in Shafa hospital which has known as a biggest center of cancer in Khuzestan province, Iran during 2005-2011.All data has entered by SPSS (version 19), descriptive statistic and adjusted odds ratio of common cancers for age and sex were calculated from multiple logistic regression model. RESULTS: From all subjects; (51% and 49%) were male and female respectively. The most frequent age group was 60-50 years and common cancers were breast 16%, colorectal 6.3%, blood 2%, lung 8% and stomach 8%. CONCLUSION: Prevalence of cancers has increased markedly with age in Khuzestan Providence. Therefore, it is essential to prevent through early prevention, using screening and identifying cases in initial stages.

Phytoextraction and phytostabilization potential of plants grown in the vicinity of heavy metal-contaminated soils: a case study at an industrial town site.

With the development of urbanization and industrialization, soils have become increasingly polluted by heavy metals. Phytoremediation, an emerging cost-effective, nonintrusive, and aesthetically pleasing technology that uses the remarkable ability of plants to concentrate elements, can be potentially used to remediate metal-contaminated sites. In this research, two processes of phytoremediation (phytoextraction and phytostabilization) were surveyed in some plant species around an industrial town in the Hamedan Province in the central-western part of Iran. To this purpose, shoots and roots of the seven plant species and the associated soil samples were collected and analyzed by measuring Pb, Fe, Mn, Cu, and Zn concentrations using ICP-AES and then calculating the biological absorption coefficient, bioconcentration factor, and translocation factor parameters for each element. The obtained results showed that among the collected plants, Salsola soda is the most effective species for phytoextraction and phytostabilization and Cirsium arvense has the potential for phytostabilization of the measured heavy metals.

Gradual tilting exposure photo and nano lithography technique.

We report a novel tilting exposure photolithography (TEL) technique where gradual pattern displacement is employed to achieve high-resolution features over large areas with reasonable exposure times. A linear array with features of the order of 100 nm has been realized using this technique with standard blue-light LED sources. TEL can be useful in the visible and ultraviolet spectra to create two-dimensional periodic structures. The created structures include the nanometric array of spots and lines. The proposed technique can be used as a writing method where complex features can be generated by moving the sample-holding leading to serpentine nanometric linear arrays.

Analysis of trace elements (Cu, Cd, and Zn) in the muscle, gill, and liver tissues of some fish species using anodic stripping voltammetry.

Heavy metal (Cu, Cd, Zn) concentration of the muscle, gill, and liver of Otolithes rubber, Pampus argenteus, Parastromateus niger, Scomberomorus commerson, and Onchorynchus mykiss are determined by anodic stripping voltammetry method. The results show that the concentration of Cu, Cd, and Zn varied between 0.44 and not detected, 0.585 and 0.001, and 0.450 and 0.005 µg/g, respectively. It is interesting that in O. mykiss, the mean value of copper concentration was more than other marine organisms of this study, while in P. niger, the mean value of copper was minimum. The results of this study indicate that in the different tissues of fish species (O. rubber, P. argenteus, P. niger, S. commerson, and O. mykiss), the concentrations of Cu, Cd, and Zn were significantly lower than the permissible FAO/WHO levels.

Prevalence of and some factors relating with unwanted pregnancy, in ahwaz city, iran, 2010.

We aimed to find the prevalence and some factors relating with unwanted pregnancy. Methods. It was a cross-sectional study on 400 randomly pregnant women, who were referring to different health centers in Ahwaz city during 2010. Data was conducted based on questionnaire, and all the analysis was performed using SPSS (version 17) statistical analysis software. Results. The prevalence of unwanted pregnancy was 26%. The percentage of unwanted pregnancy in ages more than 35 years was approximately three times more than the intended pregnancy. There were significant relationship between unwanted pregnancy and some variables such as age, number of pregnancy, number of childbirth, education status, economic status, husband's occupation, and the relationship with the spouse and contraceptive methods (P < 0.0001). Conclusion. The prevalence of unwanted pregnancy was high. To prevent unwanted pregnancy using consultation services before planning to be pregnancy, it is necessary to identify the factors relating with unwanted pregnancy.

Effect of the heavy metals on the developmental stages of ovule and seed proteins in Chenopodium botrys L. (Chenopodiaceae).

Excessive amounts of heavy metals adversely affect plant growth and development. Also, the presence of elevated levels of heavy metal ions triggers a wide range of cellular responses including changes in gene expression and synthesis of metal-detoxifying peptides. The overall objective of this research was to elucidate some microscopic effects of heavy metals on the formation, development, and structure of ovule and seed storage proteins in Chenopodium botrys L. To achieve this purpose, the surrounding area of Hame-Kasi iron and copper mine (Hamedan, Iran) was chosen as a polluted area where the amount of some heavy metals was several times higher than the natural soils. Flowers and young pods were removed from nonpolluted and polluted plants, fixed in FAA 70 and subjected to developmental studies. Our results showed that heavy metals can cause some abnormalities during the ovule developmental process. Decreasing the size of embryo sac, quick growth of inner integument, quick degradation of embryonic sac cells, accumulation of dark particles, irregularity, and even blockage of the nuclear envelope formation and increasing of embryonic sac cytoplasm concentration were the effects of heavy metals. Reduction of ovule number was also seen in the plants collected from polluted area. For protein studies, mature seeds were harvested from nonpolluted and polluted plants at the same time. Seed storage proteins (water soluble ones) were extracted and studied by sodium dodecyl sulfate-polyacrylamide gel electrophoresis after being prepared. The results revealed that there were no significant differences between seed protein bands of polluted and nonpolluted samples, but the quantity of protein bands was different, and there was a slight quantitative increase of bands with molecular mass of 35 and 15 kD and decrease of a band with molecular mass of 17 kD in the plants collected from the mine area.

Findings on the phytoextraction and phytostabilization of soils contaminated with heavy metals.

As a result of human activities such as mining, metal pollution has become one of the most serious environmental problems today. Phytoremediation, an emerging cost-effective, non-intrusive, and aesthetically pleasing technology that uses the remarkable ability of plants to concentrate elements can be potentially used to remediate metal-contaminated sites. The aim of this work was to assess the extent of metal accumulation by plants found in a mining area in Hamedan province with the ultimate goal of finding suitable plants for phytoextraction and phytostabilization (two processes of phytoremediation). To this purpose, shoots and roots of the 12 plant species and the associated soil samples were collected and analyzed by measurement of total concentrations of some elements (Fe, Mn, Zn, and Cu) using atomic absorption spectrophotometer and then biological absorption coefficient, bioconcentration factor, and translocation factor parameters calculated for each element. Our results showed that none of the plants were suitable for phytoextraction and phytostabilization of Fe, Zn, and Cu, while Chenopodium botrys, Stipa barbata, Cousinia bijarensis, Scariola orientalis, Chondrila juncea, and Verbascum speciosum, with a high biological absorption coefficient for Mn, were suitable for phytoextraction of Mn, and C. bijarensis, C. juncea, V. speciosum, S. orientalis, C. botrys, and S. barbata, with a high bioconcentration factor and low translocation factor for Mn, had the potential for the phytostabilization of this element.

Effect of prenatal pentylenetetrazol-induced kindling on learning and memory of male offspring.

Current data concerning the effects of maternal seizure during pregnancy on newborns are limited. This study was carried out to investigate the effect of prenatal pentylenetetrazol (PTZ)-induced kindling on learning and memory of offspring. Female Wistar rats were kindled with i.p. injections of 25 mg/kg of PTZ on day 13 of their pregnancy. The spatial performance and passive avoidance learning of pups were tested at 7 weeks and 12 weeks of age using Morris water maze (MWM) task and shuttle-box apparatus, respectively. We found, for the first time, that prenatal exposure to maternal seizure induced by PTZ leads to a significant impairment of learning and memory. In addition, the number of live birth was significantly lower in kindled rats compared to control. In MWM studies, the young offspring of kindled rats had poor spatial learning ability. The frequent tonic-clonic seizures in pregnancy was also associated with a poor memory as evidenced by decrease in distance swam in the target quadrant by the offspring of the kindled mother in the adulthood. Data obtained from shuttle-box studies showed that retention latencies of pups born to kindled dams were significantly reduced compared to those born to control dams. The hippocampus, amygdala and frontal cortex are very important for memory consolidation and our data suggest that subsequent developmental events are not sufficient to overcome the adverse effects of prenatal exposure to maternal seizures to these regions of the brain. These observations may have clinical implications for cognitive and memory dysfunction associated with epilepsy during pregnancy.