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Article in Russian | MEDLINE | ID: mdl-2476901

ABSTRACT

Immune disorders characteristic of the late period of craniocerebral trauma involve T-cellular, regulatory link and were represented by a reduction of T-cells count and function with disbalance in lymphocytes-helpers, increase in macrophagal and lymphoid suppressors activity susceptible to indomethacin++. The changes also include the neurosensibilization of cellular and humoral type to brain-specific++ proteins: OBM, 14-3-2, S-100. Most pronounced changes were detected in patients after severe brain concussion with focal neural changes persisting in the late period.


Subject(s)
Brain Concussion/immunology , Immunity , Adult , Autoantigens/analysis , Humans , Immunoglobulins/analysis , Leukocyte Count , Lymphocyte Activation , Middle Aged , Myelin Basic Protein/immunology , Rosette Formation , T-Lymphocytes/immunology , Time Factors
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