[Clinical laboratory characteristics of the course of local oropharyngeal diphtheria in patients with chronic tonsillitis]. / Kliniko-laboratornye osobennosti techeniia lokalizovannoi formy difterii rotoglotki na fone khronicheskogo tonsillita.

Of 115 patients admitted to hospital in 1994-1997 for stomatopharyngeal diphtheria (SPD), 41(35.7%) patients had compensated chronic tonsillitis (CT), while 17(14.8%) patients had decompensated CT. The ENT examinations carried out from the first day of the hospitalization helped to establish CT diagnostic criteria in localized form of SPD. It is shown that CT in diphtheric patients, especially decompensated CT, delays regress of local symptoms, extension of microbiocenotic spectrum and stomatopharynx contamination, prolongs carriage of diphtheric corinobacteria.

[The effect of the acetylation phenotype on the course severity and outcome of acute viral hepatitis B]. / Vliianie fenotipa atsetilirovaniia na tiazhest' techeniia i iskhody ostrogo virusnogo gepatita B.

Acetylation phenotype was studied in 70 inpatients with acute viral hepatitis B. Of them, 51 had fast and 19 slow acetylation. Fast-type acetylation was associated with mild-severe form of hepatitis B, while slow-type acetylation--with recurrences and aggravations, severe form of hepatitis. The duration of HB antigenemia in the slow-type group was twice as long as in the fast-type group. Two patients, "slow acetylators", suffered from hepatitis B in the mild-severe form, later on chronic active hepatitis (CAH) developed. In "fast" acetylators the development of CAH was not observed. Thus, determination of phenotype by acetylation may be used for prognosis of acute viral hepatitis severity as well as for identification of high-risk groups and planning policy of follow-up.