ABSTRACT
Buske-Lowenstein tumour (BLT) is a giant condyloma acuminata characterized by a potential for malignant transformation and invasion and recurrence after treatment. It is a rare viral disease, essentially transmitted by sexual intercourse. The objective of this study was to evaluate the epidemiology, clinical features, classification and prognosis of this disease and to outline the treatment modalities. The authors report 3 unusual cases of Buske-Lowenstein tumour involving the scrotum in 2 cases and associated with malignant transformation in 1 case. All three patients (1 woman and two men) presented a history of high-risk sexual behaviour. BLT was confirmed by biopsy and was treated by complete surgical resection. The postoperative course was uneventful without recurrence. Treatment has not been clearly defined and is essentially based on surgery. Sexual education and early treatment of condylomatous lesions can improve the prognosis of this disease. In the light of these cases, the authors emphasize the importance of prevention for all sexually transmissible infections based on sexual education.
