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Tsitol Genet ; 28(5): 73-7, 1994.
Article in Russian | MEDLINE | ID: mdl-7900201

ABSTRACT

Restriction fragment length polymorphism of the apo-B gene at the Xbal restriction site was detected. The association between RFLP of the apo-B gene and the level of lipid metabolism indices was revealed. The levels of total cholesterol LDLP CH and atherogenicity coefficient were significantly higher in homozygotes with this restriction site (X2X2) than in homozygotes X1X1 and heterozygotes.


Subject(s)
Apolipoproteins B/genetics , Chromosomes, Human, Pair 2 , Lipids/blood , Myocardial Ischemia/blood , Myocardial Ischemia/genetics , Polymorphism, Restriction Fragment Length , Adult , DNA/blood , Genotype , Humans , Risk Factors
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