ABSTRACT
Hyperkinetic atactic syndrome, an atypical neurologic disorder of a chemical origin, was reported in connection with trinitrotoluene-induced melanoderma. Decreased level of urinary 17-hydroxycorticoids stresses the failure of one biochemical link in melanin synthesis, but proves the same pathogenic origin of both melanopathy manifestations. Antioxidant therapy in the pathogenesis treatment of melanoderma is considered valuable.
Subject(s)
Central Nervous System Diseases/chemically induced , Melanosis/chemically induced , Occupational Exposure , Trinitrotoluene/poisoning , 17-Hydroxycorticosteroids/urine , Antioxidants/therapeutic use , Central Nervous System Diseases/diagnosis , Central Nervous System Diseases/drug therapy , Central Nervous System Diseases/urine , Humans , Male , Melanosis/diagnosis , Melanosis/drug therapy , Melanosis/urine , Middle Aged , SyndromeABSTRACT
The hand joint is a multi-joint formation, including the wrist, carpal, intercarpal, carpometacarpal, intermetacarpal, distal radioulnar joints. Features of hand joint and periarticular tissue disease were studied in 536 workers exposed to local vibration and functional overstrain. The most prevalent diseases are arthroses with deformation of the wrist, radiocarpal, carpometacarpal joints, often with involvement of the triangular fibrous disk and carpals, periarthroses of the hand joint with compression neuropathy of the median and ulnar nerves.
Subject(s)
Hand , Occupational Diseases/etiology , Osteoarthritis/etiology , Periarthritis/etiology , Stress, Physiological/complications , Vibration/adverse effects , Adult , Chronic Disease , Humans , Joint Diseases/diagnosis , Joint Diseases/etiology , Middle Aged , Nerve Compression Syndromes/diagnosis , Nerve Compression Syndromes/etiology , Occupational Diseases/diagnosis , Osteoarthritis/diagnosis , Periarthritis/diagnosis , Stress, Physiological/diagnosisABSTRACT
Features of forming and course of ulnar nerve compression neuropathy in the cubital and Guyin's canals were studied in 86 subjects, suffering from occupational diseases of the arms due to vibration and functional overstrain. Compression neuropathy of the ulnar nerve aggravates the vibration disease and arm disorders caused by functional overstrain--increases frequency, intensity and duration of paroxysmal paleness of the IV-V fingers, aggravates paresthesia, hypalgesia and hypothermia of the ulnar antebrachium, markedly decrease power of the hand, which must be taken into account when solving exert problems and carrying out treatment and rehabilitation.
