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Biull Eksp Biol Med ; 89(4): 415-7, 1980 Apr.
Article in Russian | MEDLINE | ID: mdl-6966945

ABSTRACT

Cellular composition of the bone marrow, spleen and peripheral blood was studied after 6-hour immobilization on the back in experiments on 4 groups of (CBAxC57BL)F1 mice with varying degree of T lymphocyte deficiency (thymectomy, sham thymectomy, administration of antilymphocytic serum, B mice). The evidence obtained shows that the "lymphoid peak" recorded in the bone marrow during stress is likely to be formed at the expense of T and B lymphocyte migration from the peripheral lymphoid organs. The data have been also obtained, indicating that T lymphocytes migrating to the bone marrow during the first 6-9 hours after the exposure to stress may participate in granulocytopoiesis activation.


Subject(s)
B-Lymphocytes/immunology , Hematopoietic System/pathology , Stress, Physiological/immunology , T-Lymphocytes/immunology , Animals , Antilymphocyte Serum/pharmacology , Bone Marrow/immunology , Bone Marrow/pathology , Cell Count , Cell Movement , Hybridization, Genetic , Mice , Mice, Inbred C57BL , Mice, Inbred CBA , Spleen/pathology , Stress, Physiological/pathology , Thymectomy
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