[Palatine tonsils and immunity. VIII. Soluble factors produced by lymphocytes of the palatine tonsils and other lymphoid formations in rabbits]. / Nebnye mindaliny i immunitet. Soobshchenie VIII. Rastvorimye faktory, produtsiruemye limfotsitami nebnykh mindalin i drugikh limfoidnykh obrazovanii krolikov

A comparison was made of the activity of solbule factors produced by thelymphocytes of the palatine tonsils, the appendix, the spleen and thelymph nodes of rabbits in stimulation with a specific antigen (complete antigen of streptococcus, group A) and PHA. The blastogenic factor produced by the lymphoid cells of the spleen and the lymph nodes was highly active. Lymphocytes of the palatine tonsils and of the appendix produced a factor withlow activity after PHA stimulation. A factor intensifying the transformation in the presence of a complete streptococcus antigen was produced by lymphocytes of the spleen and the lymph nodes of the immunized animals. The lymphocytes of the palatine tonsils and the appendix failed to produce this factor.

[Palatine tonsils and immunity. IV. Lymphocyte blast transformation in various lymphoid organs of animals immunized with microbial antigens]. / Nebnye mindaliny i immunitet. Soobshchenie IV. Blasttransformatsiia limfotsitov razlichnykh limfoidnykh organov zhivotnykh, immunizirovannykh mikrobnymi antigenami

For the purpose of ascertaining the peculiarities of cellular differentiation of lymphoid cells of the palatine tonsils experiments were conducted on rabbits immunized intravenously and subcutaneously with streptococcus and paratyphoid B antigens; a study was made (in the blast-transformation reaction) of a comparative response of the lymphocytes of the palatine tonsils, the thymus, the spleen, the appendix and the regional lymph node. In case of stimulation with the specific microbial antigens and PHA the proliferative response was greater in the culture of the splenic lymphocytes and the regional lymph node than in the culture of the lymphocytes of the palatine tonsils and the appendix. The thymus lymphocytes responded to PHA only. A conclusion was drawn that the paratyphoid B and streptococcus antigens penetrating into the lymphoid tissue by hematogenic route stimulated a relatively low percentage of lymphocytes of the palatine tonsils and the appendix in comparison with the regional lymph node and the spleen.