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1.
Aesthet Surg J ; 44(5): 556-564, 2024 Apr 04.
Article in English | MEDLINE | ID: mdl-37972242

ABSTRACT

BACKGROUND: TikTok is a powerful and popular source of patient education. However, the lack of content regulation raises concerns about the spread of medical misinformation. OBJECTIVES: We aimed to analyze the source, content, quality, and reliability of TikTok posts focusing on surgical and nonsurgical cosmetic treatments for men. METHODS: A search was conducted on TikTok with 16 popular hashtags related to male cosmetic procedures. The top 25 male-focused videos from each hashtag were chosen for analysis. Videos were categorized by content creator, video type, and descriptive metrics. Educational videos were evaluated for quality with the validated modified DISCERN (mDISCERN) score and the Patient Education Materials Assessment Tool (PEMAT) scale. Statistical analysis was performed with univariate and linear regression models. RESULTS: The included 399 videos totaled 389 million views, 16.4 million likes, 174,594 comments, and 586,743 shares. Most videos were uploaded by plastic and reconstructive surgeons (38.3%). A significant number (38%) of videos by physicians were posted by international physicians, with videos by United States physicians receiving fewer views, comments, and shares than videos posted by international physicians. Patient experience was the most common video category (48.9%). Educational videos had low overall quality, with physician-created videos demonstrating higher DISCERN and PEMAT scores but lower engagement compared to nonphysician videos. CONCLUSIONS: The quality of TikTok videos on male cosmetic surgery was generally low, emphasizing the importance of accurate information dissemination by physicians on social media. The strong presence of international physicians highlights the potential implications of social media on medical tourism.


Subject(s)
Plastic Surgery Procedures , Social Media , Surgery, Plastic , Male , Humans , Reproducibility of Results , Benchmarking
2.
Adv Mater ; 34(49): e2206876, 2022 Dec.
Article in English | MEDLINE | ID: mdl-36100349

ABSTRACT

The DNA tensegrity triangle is known to reliably self-assemble into a 3D rhombohedral crystalline lattice via sticky-end cohesion. Here, the library of accessible motifs is expanded through covalent extensions of intertriangle regions and sticky-end-coordinated linkages of adjacent triangles with double helical segments using both geometrically symmetric and asymmetric configurations. The molecular structures of 18 self-assembled architectures at resolutions of 3.32-9.32 Å are reported; the observed cell dimensions, cavity sizes, and cross-sectional areas agree with theoretical expectations. These data demonstrate that fine control over triclinic and rhombohedral crystal parameters and the customizability of more complex 3D DNA lattices are attainable via rational design. It is anticipated that augmented DNA architectures may be fine-tuned for the self-assembly of designer nanocages, guest-host complexes, and proscriptive 3D nanomaterials, as originally envisioned. Finally, designer asymmetric crystalline building blocks can be seen as a first step toward controlling and encoding information in three dimensions.


Subject(s)
DNA
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