[Labor strategies of graduates of medical educational institutions: predicted risks of the medical industry].

The article presents the results of a study of the labor strategies of youth included in the personnel reproduction of regional health care. The authors of the article consider the results of a complex sociological study of graduates of educational medical organizations and specialized medical classes (focus group studies, target survey; n = 1027). The research made it possible to answer questions about the dynamics of professional motivation of young people, to determine labor strategies and reasons for choosing in life planning. The article proposes a factor model of decision-making when choosing a workplace by graduates of medical specialties, gives an assessment of existing workplaces in the regional health care system, conducts an audit of the need for stimulating measures to retain and secure young personnel in the medical industry. The results of the research made it possible to determine the risks of youth labor strategies as a personnel reserve of medicine and to propose directions for their leveling and correction of the situation. An important result of scientific research can be considered the proposed diagnostic complex itself, which makes it possible to establish the dynamics of indicators during subsequent measurements (motivational transformation, change in migration aspirations and labor choice) and to determine the effectiveness of the measures and decisions taken. The result and scientific result of the article is the conclusion about the lack of orientation to the key problems of the implementation of labor strategies by graduates of educational medical organizations from the branch administration system, early pre-professional burnout of young personnel, the problem of regional public opinion regarding the prestige of the medical profession and effective labor strategies of future doctors.

[Microbiological profile of postoperative infection in current oncology surgery]. / Mikrobiologicheskii profil' posleoperatsionnoi infektsii v sovremennoi onkokhirurgii.

AIM: To analyze in-hospital infection in oncology center within 2012-2016. MATERIAL AND METHODS: There were 98 patients with nosocomial infection who underwent surgery for malignancies. Microbiological examination of biological materials was carried out by appropriate laboratories according to generally accepted methods. RESULTS: Mono- and polymicrobial infection was observed in 58 and 42% of cases. Staphylococcus aureus was the most common agent in patients with microbial infection. Minimal inhibitory concentration of vancomycin (MIC) ≥1.0 µg/ml was revealed in 60% of microbes. Microbial agents isolated were resistant to antibacterial drugs used to prevent postoperative infectious complications. CONCLUSION: In-hospital infection was accompanied by staphylococci as a rule. Causative agents of nosocomial infections are usually resistant to conventional antibacterial drugs. Moreover, 60.1% of microbes had minimal inhibitory concentration of vancomycin ≥1.0 µg/ml that indicated the need for alternative therapeutic agents.

Studies of antimutagenic effects of vitamins A and C in humans.

We studied antimutagenic effects of vitamins A and C (in recommended daily doses for 30 days) and their effects on the kinetics of human buccal epitheliocytes. Buccal swab specimens were collected in 29 students before and after vitamin course. The cytogenetic parameters (cells with micronuclei and protrusions) and parameters of proliferation (binuclear cells and cells with double nuclei) and nucleus destruction (karyopyknosis, karyorrhexis, karyolysis, etc.) were analyzed. The levels of cells with micronuclei and total level of cytogenetic disorders decreased by 38% after vitamin course, which confirmed their antimutagenic effect. A slight increase in the percentage of apoptotic cells seemed to reflect more active process of elimination of genetically damaged cells.