Highly Sensitive and Reliable Piezoresistive Strain Sensor Based on Cobalt Nanoporous Carbon-Incorporated Laser-Induced Graphene for Smart Healthcare Wearables.

The development of highly sensitive, reliable, and cost-effective strain sensors is a big challenge for wearable smart electronics and healthcare applications, such as soft robotics, point-of-care systems, and electronic skins. In this study, we newly fabricated a highly sensitive and reliable piezoresistive strain sensor based on polyhedral cobalt nanoporous carbon (Co-NPC)-incorporated laser-induced graphene (LIG) for wearable smart healthcare applications. The synergistic integration of Co-NPC and LIG enables the performance improvement of the strain sensor by providing an additional conductive pathway and robust mechanical properties with a high surface area of Co-NPC nanoparticles. The proposed porous graphene nanosheets exploited with Co-NPC nanoparticles demonstrated an outstanding sensitivity of 1,177 up to a strain of 18%, which increased to 39,548 beyond 18%. Additionally, the fabricated sensor exhibited an ultralow limit of detection (0.02%) and excellent stability over 20,000 cycles even under high strain conditions (10%). Finally, we successfully demonstrated and evaluated the sensor performance for practical use in healthcare wearables by monitoring wrist pulse, neck pulse, and joint flexion movement. Owing to the outstanding performance of the sensor, the fabricated sensor has great potential in electronic skins, human-machine interactions, and soft robotics applications.

Hysteresis-Free Double-Network Hydrogel-Based Strain Sensor for Wearable Smart Bioelectronics.

Hydrogel-based electronics have attracted substantial attention in the field of biological engineering, energy storage devices, and soft actuators due to their resemblance to living tissues, biocompatibility, tunable softness, and consolidated structures. However, combining the properties of quick resilience, hysteresis-free, and robust mechanical properties in physically cross-linked hydrogels is still a great challenge. Herein, we present a vinyl hybrid silica nanoparticle (VSNPs)/polyacrylamide (PAAm)/alginate double-network hydrogel-based strain sensor with the characteristics of quick resilience, hysteresis-free, and a low limit of detection (LOD). The physical cross-linking among PAAm chains and covalent cross-linking between PAAm, alginate, and N,N-methylenebisacrylamide chains promotes excellent mechanical properties. Moreover, the incorporation of VSNPs reinforces the mechanical strength by the dynamic cross-linking of the PAAm network to maintain the integrity of the hydrogel and works as a stress buffer to dissipate energy. The as-prepared hydrogel-based sensor exhibits a strain sensitivity (i.e., gauge factor) of 1.73 (up to 100% strain), a response time of 0.16 s, an ultra-low electrical hysteresis of 2.43%, and a low LOD of 0.4%. The outstanding properties of the hydrogel are further used to illustrate the utility of the sensor in e-skin, ranging from low-strain applications, such as carotid pulse and artificial sound detection, to large bending applications, such as sign language translations. In addition, an efficient and cost-effective synthesis of double-network hydrogel that can overcome the bottleneck of the electromechanical properties of single network hydrogel has potential prospects in soft actuators, tissue engineering, and various biomedical applications.

Hydrogen-Bond-Triggered Hybrid Nanofibrous Membrane-Based Wearable Pressure Sensor with Ultrahigh Sensitivity over a Broad Pressure Range.

Recently, flexible capacitive pressure sensors have received significant attention in the field of wearable electronics. The high sensitivity over a wide linear range combined with long-term durability is a critical requirement for the fabrication of reliable pressure sensors for versatile applications. Herein, we propose a special approach to enhance the sensitivity and linearity range of a capacitive pressure sensor by fabricating a hybrid ionic nanofibrous membrane as a sensing layer composed of Ti3C2Tx MXene and an ionic salt of lithium sulfonamides in a poly(vinyl alcohol) elastomer matrix. The reversible ion pumping triggered by a hydrogen bond in the hybrid sensing layer leads to high sensitivities of 5.5 and 1.5 kPa-1 in the wide linear ranges of 0-30 and 30-250 kPa, respectively, and a fast response time of 70.4 ms. In addition, the fabricated sensor exhibits a minimum detection limit of 2 Pa and high durability over 20 000 continuous cycles even under a high pressure of 45 kPa. These results indicate that the proposed sensor can be potentially used in mobile medical monitoring devices and next-generation artificial e-skin.

Smart bandage with integrated multifunctional sensors based on MXene-functionalized porous graphene scaffold for chronic wound care management.

Three-dimensional (3D) porous laser-guided graphene (LGG) electrodes on elastomeric substrates are of great significance for developing flexible functional electronics. However, the high sheet resistance and poor mechanical properties of LGG sheets obstruct their full exploitation as electrode materials. Herein, we applied 2D MXene nanosheets to functionalize 3D LGG sheets via a C-O-Ti covalent crosslink to obtain an LGG-MXene hybrid scaffold exhibited high conductivity and improved electrochemistry with fast heterogeneous electron transfer (HET) rate due to the synergistic effect between LGG and MXene. Then we transferred the obtained hybrid scaffold onto PDMS to engineer a smart, flexible, and stretchable multifunctional sensors-integrated wound bandage capable of assessing uric acid (UA), pH, and temperature at the wound site. The integrated UA sensor exhibited a rapid response toward UA in an extended wide range of 50-1200 µM with a high sensitivity of 422.5 µA mM-1 cm-2 and an ultralow detection limit of 50 µM. Additionally, the pH sensor demonstrated a linear Nernstian response (R2 = 0.998) with a high sensitivity of -57.03 mV pH-1 in the wound relevant pH range of 4-9. The temperature sensor exhibited a fast and stable linear resistive response to the temperature variations in the physiological range of 25-50 °C with an excellent sensitivity and correlation coefficient of 0.09% °C-1 and 0.999, respectively. We anticipate that this stretchable and flexible smart bandage could revolutionize wound care management and have profound impacts on the therapeutic outcomes.

Wearable Capacitive Pressure Sensor Based on MXene Composite Nanofibrous Scaffolds for Reliable Human Physiological Signal Acquisition.

In recent years, highly sensitive pressure sensors that are flexible, biocompatible, and stretchable have attracted significant research attention in the fields of wearable electronics and smart skin. However, there has been a considerable challenge to simultaneously achieve highly sensitive, low-cost sensors coupled with optimum mechanical stability and an ultralow detection limit for subtle physiological signal monitoring devices. Targeting aforementioned issues, herein, we report the facile fabrication of a highly sensitive and reliable capacitive pressure sensor for ultralow-pressure measurement by sandwiching MXene (Ti3C2Tx)/poly(vinylidene fluoride-trifluoroethylene) (PVDF-TrFE) composite nanofibrous scaffolds as a dielectric layer between biocompatible poly-(3,4-ethylenedioxythiophene) polystyrene sulfonate /polydimethylsiloxane electrodes. The fabricated sensor exhibits a high sensitivity of 0.51 kPa-1 and a minimum detection limit of 1.5 Pa. In addition, it also enables linear sensing over a broad pressure range (0-400 kPa) and high reliability over 10,000 cycles even at extremely high pressure (>167 kPa). The sensitivity of the nanofiber-based sensor is enhanced by MXene loading, thereby increasing the dielectric constant up to 40 and reducing the compression modulus to 58% compared with pristine PVDF-TrFE nanofiber scaffolds. The proposed sensor can be used to determine the health condition of patients by monitoring physiological signals (pulse rate, respiration, muscle movements, and eye twitching) and also represents a good candidate for a next generation human-machine interfacing device.

MoS2-Decorated Laser-Induced Graphene for a Highly Sensitive, Hysteresis-free, and Reliable Piezoresistive Strain Sensor.

Advancement of sensing systems, soft robotics, and point-of-care testing requires the development of highly efficient, scalable, and cost-effective physical sensors with competitive and attractive features such as high sensitivity, reliability, and preferably reversible sensing behaviors. This study reports a highly sensitive and reliable piezoresistive strain sensor fabricated by one-step carbonization of the MoS2-coated polyimide film to obtain MoS2-decorated laser-induced graphene. The resulting three-dimensional porous graphene nanoflakes decorated with MoS2 exhibit stable electrical properties yielding a reliable output for longer strain/release cycles. The sensor demonstrates high sensitivity (i.e., gauge factor, GF ≈1242), is hysteresis-free (∼2.75%), and has a wide working range (up to 37.5%), ultralow detection limit (0.025%), fast relaxation time (∼0.17 s), and a highly stable and reproducible response over multiple test cycles (>12 000) with excellent switching response. Owing to the outstanding performances of the sensor, it is possible to successfully detect various subtle movements ranging from phonation, eye-blinking, and wrist pulse to large human-motion-induced deformations.

Ultrasensitive Interfacial Capacitive Pressure Sensor Based on a Randomly Distributed Microstructured Iontronic Film for Wearable Applications.

The rapid development of pressure sensors with distinct functionalities, notably, with increased sensitivity, fast response time, conformability, and a high degree of deformability, has increased the demand for wearable electronics. In particular, pressure sensors with an excellent sensitivity in the low-pressure range (<2 kPa) and a large working range simultaneously are strongly demanded for practical applications in wearable electronics. Here, we demonstrate an emerging class of solid polymer electrolyte obtained by incorporating a room-temperature ionic liquid, 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide with poly(vinylidene fluoride- co-hexafluoropropylene) as a high-capacitance dielectric layer for interfacial capacitive pressure sensing applications. The solid polymer electrolyte exhibits a very high interfacial capacitance by virtue of mobile ions that serve as an electrical double layer in response to an electric field. The randomly distributed microstructures created on the solid electrolyte help the material to elastically deform under pressure. Moreover, the interfacial capacitance is improved by utilizing a highly conductive porous percolated network of silver nanowires reinforced with poly(dimethylsiloxane) as the electrodes. An ultrahigh-pressure sensitivity of 131.5 kPa-1, a low dynamic response time of ∼43 ms, a low limit of detection of 1.12 Pa, and a high stability for over 7000 cycles are achieved. Finally, we demonstrate the application of the sensor for international Morse code detection, artery pulse detection, and eye blinking. Owing to the ultrahigh sensitivity, the as-fabricated sensor will have great potential for wearable devices in health status monitoring, motion detection, and electronic skin.