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1.
J Strength Cond Res ; 38(5): 924-931, 2024 May 01.
Article in English | MEDLINE | ID: mdl-38608041

ABSTRACT

ABSTRACT: Yao, X, Austerberry, A, Bishop, C, Wilson, L, Chiang, C-Y, and Turner, A. Seasonal variation and positional differences in anthropometry, strength, and power characteristics in English premiership women's rugby union players. J Strength Cond Res 38(5): 924-931, 2024-Women's rugby is a collision sport that relies heavily on body composition and physical characteristics of strength and power to achieve competitive success. Furthermore, the seasonal nature presents a variety of physical challenges that can cause fluctuations in a player's physical development. Therefore, the purpose of this study was to determine the differences in anthropometry, strength, and power characteristics between forwards and backs in women's rugby union athletes in England and to identify changes throughout a season. Forty-seven players were recruited from the English premiership women's rugby during the 2020-2021 season. Players were split into forwards and backs and underwent body composition testing by dual-energy X-ray absorptiometry and strength and power tests (countermovement jump, drop jump [DJ], and isometric midthigh pull) on 3 separate occasions (preseason, midseason, postseason). Overall, forwards had significantly ( p < 0.01) higher body mass, fat mass, lean mass [LM], bone mineral content, and take off momentum, and backs had significantly higher ( p < 0.01, d > 0.5) jump height, reactive strength, and shorter DJ contact time. When observing seasonal changes, there were statistically significant differences ( p < 0.01) or moderate-to-large practical differences ( d > 0.5) in LM, reactive strength index modified, time to take-off, and DJ flight time [FT] among forwards when comparing 3 testing time frames. For backs, statistically significant differences ( p < 0.01) or moderate-to-large practical differences ( d > 0.5) were reported in LM and DJ FT throughout the season. In conclusion, the strength and power testing and characteristics shown in this study could support coaches and junior women's rugby athletes to have a basic understanding of English premiership physical standards.


Subject(s)
Anthropometry , Body Composition , Muscle Strength , Seasons , Humans , Female , Muscle Strength/physiology , Young Adult , Body Composition/physiology , England , Adult , Football/physiology , Athletic Performance/physiology , Absorptiometry, Photon , Athletes , Rugby/physiology
2.
Article in English | MEDLINE | ID: mdl-33680060

ABSTRACT

Despite minoxidil and finasteride already being approved by the Food and Drug Administration (FDA) for the treatment of hair loss, it is important to identify new and innovative treatments for hair loss, such as looking for a solution in Chinese herbal medicine. One such treatment to consider is BeauTop (BT), whose primary ingredients include Panax japonicus (T.Nees), C.A. Mey. (Araliaceae), Astragalus membranaceus (Fisch) Bunge (Fabaceae), Angelica sinensis (Oliv.) Diels (Apiaceae), Ligustrum lucidum W.T. Aiton (Oleaceae), Rehmannia glutinosa (Gaertn.) DC. (Plantaginaceae), and Eclipta prostrata (L.) L. (Compositae). The aim of this study was to evaluate whether BT can promote hair growth in C57BL/6 mice and to investigate hair coverage, the expression of vascular endothelial growth factor (VEFG), and the numbers of hair follicles in growth phase after oral administration. A total of 12 C57BL/6 mice were divided into two groups: control group and treatment group BT. BT was administered orally as an extract at a volume of 0.6 g/kg. The control group was treated with distilled water. Each group was treated once a day for 12 consecutive days. To observe the expression of VEGF distribution, the number of hair follicles and the hair coverage were examined on days 4, 8, and 12. By comparing the treatment group and control group, we found that VEGF in the BT group on day 8 presented with a higher area percentage than the control group (p value = 0.003). Hair follicle counting results showed that the BT group was significantly higher than the control group on day 8 (p value = 0.031). Furthermore, hair coverage was shown to be significantly increased in the treatment group BT on day 8 (p value = 0.013). Taken together, these results suggest that Chinese medicine (BT) possesses the potential effect of promoting hair growth through VEGF expression. VEGF is considered the most important mediator for the process of angiogenesis involved in hair growth development.

3.
Exp Ther Med ; 13(1): 194-202, 2017 Jan.
Article in English | MEDLINE | ID: mdl-28123489

ABSTRACT

The aim of the present study was to evaluate the treatment effects of BeauTop in alopecia by observing its effectiveness in improving androgenetic alopecia. Hair growth was observed using a dermatoscope and clinical photos, and was scored by three dermatologists. Dermatologists evaluated and selected suitable participants for this study using the Norwood scale or Ludwig scale. A total of 40 participants with androgenetic alopecia were recruited in this study, and 32 participants completed the 6-month trial. The results revealed that in the BeauTop treatment group, 9/17 participants (52.9%) showed increased hair growth. Changes in hair growth were as follows: No change, 47.1% patients; minimally improved, 5.9% patients; moderately improved, 29.4% patients; and significantly improved, 17.6% patients. In the placebo group, 2/15 participants (13%) showed increased hair growth. A Chi-square test was performed and attained a value of 0.01

4.
Carbohydr Polym ; 119: 18-25, 2015 Mar 30.
Article in English | MEDLINE | ID: mdl-25563940

ABSTRACT

A photoresponsive hybrid alginate hydrogel was successfully prepared by Ca(2+)-mediated crosslinking reaction with a mixture of ß-cyclodextrin-grafted alginate (ß-CD-Alg) and diazobenzene-modified poly(ethylene glycol) (Az2-PEG). The water-soluble Az2-PEG exhibits efficient trans-to-cis isomerization of the terminal azobenzene moieties under UV-light irradiation and readily switched back to the initial trans state under visible light. Because of low affinity between ß-CD and cis-Az, the host-guest inclusion complex formed by ß-CD and trans-Az gradually dissociates under UV-light exposure. Accordingly, the bulk gel exhibits substantial photo-induced transformation in gel morphology by the appearance of significant comb-like cavities. This photosensitive behavior accompanied by the structural degradation enables the rapid release of entrapped dye molecules under UV light stimulus. Moreover, an incident light with higher power and mild acidic environment are capable of accelerating the photo-triggered release, thus allowing the potential applications toward acute wound healing.


Subject(s)
Alginates/chemical synthesis , Hydrogel, Polyethylene Glycol Dimethacrylate/chemical synthesis , Ultraviolet Rays , Alginates/chemistry , Delayed-Action Preparations , Glucuronic Acid/chemical synthesis , Glucuronic Acid/chemistry , Hexuronic Acids/chemical synthesis , Hexuronic Acids/chemistry , Hydrogel, Polyethylene Glycol Dimethacrylate/chemistry , Hydrogen-Ion Concentration , Microscopy, Electron, Scanning , Polyethylene Glycols/chemical synthesis , Polyethylene Glycols/chemistry , Rhodamines/chemistry , Spectrometry, Fluorescence , Spectroscopy, Fourier Transform Infrared , beta-Cyclodextrins/chemistry
5.
Ann Allergy Asthma Immunol ; 107(6): 501-9, 2011 Dec.
Article in English | MEDLINE | ID: mdl-22123379

ABSTRACT

BACKGROUND: Danggui Buxue Tang (DBT), an herbal formula containing Angelica sinensis (AS) and Astragalus membranaceus (AM) (AS:AM = 1:5, designated as DBT1 here), has been used in Chinese medicine to enhance qi and blood circulation. In addition, DBT has served as a treatment for atopic dermatitis in dogs in Taiwan. It also may improve fibrosis in a rat model of pulmonary fibrosis. OBJECTIVE: In this study, we evaluated the effect of oral administration of DBT1 in asthma in ovalbumin (OVA)-sensitized mice. METHODS: Female BALB/c mice were sensitized and challenged with OVA and fed with DBT1 or modified formulas of DBT1, designated as DBT2 (AS:AM = 1:1) and DBT3 (AS:AM = 5:1), from days 21 to 27. RESULTS: DBT1 suppressed airway hyperresponsiveness and eosinophil infiltration in bronchoalveolar lavage fluid (BALF) and lung, and Th2-associated cytokines and chemokines were inhibited in BALF. In addition, levels of OVA-immunoglobulin E (IgE) also were suppressed in serum. However, treatment with DBT2 or DBT3 showed no improved effects relative to DBT1 in treating asthmatic symptoms. CONCLUSIONS: These results suggest that orally administered DBT (DBT1) can reduce allergic reactions in OVA-sensitized mice.


Subject(s)
Asthma/drug therapy , Asthma/immunology , Bronchial Hyperreactivity/drug therapy , Bronchial Hyperreactivity/immunology , Drugs, Chinese Herbal/pharmacology , Animals , Asthma/blood , Bronchial Hyperreactivity/blood , Bronchoalveolar Lavage Fluid/cytology , Bronchoalveolar Lavage Fluid/immunology , Cytokines/blood , Disease Models, Animal , Female , Immunoglobulin E/blood , Immunohistochemistry , Mice , Mice, Inbred BALB C , Ovalbumin/immunology , Random Allocation
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