Egalitarian penalty or reward? A longitudinal study of adolescent gender attitudes and adulthood income.

Studies often attribute the persistent gender pay gap to different labor force experiences between men and women. Yet, attitudes formed in earlier life stages also critically shape individual outcomes. Using longitudinal data from Taiwan, this study examines whether and how adolescents' gender attitudes are related to income in young adulthood. We test two pathways that mediate this relationship at different time points: the attitude continuity pathway from adolescence to young adulthood, hypothesized by the path-dependence theory, and the occupational pathway during young adulthood, hypothesized by the gender socialization perspective. The findings show that girls with egalitarian attitudes are rewarded, as both pathways facilitate higher income in adulthood. However, boys with egalitarian attitudes are simultaneously rewarded and penalized based on different occupational characteristics, resulting in an overall null effect. This study highlights the importance of adolescent gender attitudes and the differential consequences for men and women in the labor market.

Overexpression of Kynurenine 3-Monooxygenase Correlates with Cancer Malignancy and Predicts Poor Prognosis in Canine Mammary Gland Tumors.

Tumor biomarkers are developed to indicate tumor status, clinical outcome, or prognosis. Since currently there are no effective biomarkers for canine mammary tumor (CMT), this study intended to verify whether kynurenine 3-monooxygenase (KMO), one of the key enzymes involved in tryptophan catabolism, is competent for predicting prognosis in patients with CMT. By investigating a series of 86 CMT clinical cases, we found that both gene and protein expression of KMO discriminated malignant from benign CMTs and was significantly higher in stage IV and V tumors than in lower-stage CMTs. About 73.7% of malignant CMTs showed strong expression of KMO which correlated with lower overall survival rates in patients. Further, downregulation of KMO activity significantly inhibited cell proliferation of CMT cells. Taken together, the findings indicated that KMO is a potential biomarker for tumor diagnosis, and this might open up new perspectives for clinical applications of CMT.

Do grandparents matter? A multigenerational perspective on educational attainment in Taiwan.

In response to the growing interest in multigenerational effects, we investigate whether grandparents' education affects grandchildren's transitions to academic high school and university in Taiwan. Drawing on social capital literature, we consider potential heterogeneity of the grandparent effect by parents' characteristics and propose that grandparents' education yields differential effects depending on parents' education. Our results show tenuous effects of grandmother's and grandfather's years of schooling, net of parents' education. However, the positive interaction effects between grandparents' and parents' years of schooling indicate that grandparents' additional years of schooling are more beneficial to students with more educated parents than for students with less educated parents. The diverging gap in the likelihood of attending academic high school or university between students with parents in higher and lower ends of the educational hierarchy, along with increased levels of grandparents' education, supports our hypothesis that grandparents' education augments educational inequality by parents' education.

It's Not Just About the Money: Gender and Youth Migration from Rural China.

Statistics suggest that young men and women in China migrate at almost equal numbers, but we know less about gender differences in the decision to migrate. We examine the factors associated with the decision to migrate and the rationales given by young migrants. Our results are consistent with previous figures and show no overall gender differences in susceptibility to migration. However, we find that sibship structure operates differently on the decisions of boys and girls. Young men were more likely to report that they had moved for purposes of starting a business or personal development than young women, while young women were more likely to report that they had moved to support the tuition of a family member. We argue that the simple gender parity with respect to the number of migrants masks important differences in the circumstances and personal motivations for migration for men and women.

Surfection: a new platform for transfected cell arrays.

Efficient high-throughput expression of genes in mammalian cells can facilitate large-scale functional genomic studies. Towards this aim, we developed a simple yet powerful method to deliver genes into cells by cationic polymers on the surface of substrates. Transfection can be achieved by directly contacting nucleic acid-cell mixtures with the cationic substrates, e.g. polyethylenimine/collagen-coated wells. This single-step matrix-surface- mediated transfection method, termed 'surfection', can efficiently deliver multiple plasmids into cells and can successfully assay siRNA-mediated gene silencing. This technology represents the easiest method to transfer combinations of genes in large-scale arrays, and is a versatile tool for live-cell imaging and cell-based drug screening.