ABSTRACT
: Introdução: O HIV e SIDA é um problema de saúde pública global, responsável por cerca de 32.7 milhões de mortes de doenças relacionadas à SIDA desde o início da epidemia até o final de 2019, comprometendo a saúde, a força de produção e produtividade. Esse cenário tende a ser mais grave, quando se trata de forças militares, cuja a responsabilidade da defesa e manutenção da paz, recai sobre eles. O objectivo foi avaliar o perfil clinico-epidemiológico e factores associados a não supressão viral em pacientes vivendo com HIV/SIDA assistidas no Centro Integrado de Tratamento no Hospital Militar de Maputo (CITRA/HMM). Métodos: Tratou-se de um estudo transversal analítico com uma abordagem quantitativa, utilizando dados secundários de pacientes em seguimento entre os anos de 2019-2020 no CITRA/HMM. A amostra foi composta por 9.015 indivíduos com idade igual ou superiora 15 anos de idade. A analise de dados foi feita com pacote estatístico STATA versão 16, onde recorreu-se os testes Qui-quadrado de Pearson e a razão de chances/OR com Intervalos de Confiança/IC de 95% e p<0,05, para verificar as diferenças entre às proporções e a associação entre as variáveis em análise, considerando como desfecho o estado de supressão viral: suprimido (<1000 cópias de RNA do HIV/ml) e não suprimido (≥1000 cópias de RNA do HIV/ml). Para o modelo de regressão logística múltipla, apenas foram seleccionadas as variáveis que se mostraram estatisticamente significativas na análise bivariada. Resultados: Dos 9.105 indivíduos inclusos na análise, 4.808 (52,8%) eram do sexo feminino e 1.235 (13,6%) eram militares. A média de idade foi de 47,9 anos (DP±12,1), sendo o grupo etário mais prevalente composto por indivíduos com idades entre 25 e 59 anos, totalizando 7.297 (80,2%) participantes. Entre os analisados, 5.395 (53,3%) tinham resultados de última carga viral, e destes, 4.148 (76,9%) tinham a carga viral suprimida. Embora a maior proporção de supressão viral tenha sido verificada em civis, quando ajustada, essa diferença não demonstrou significância estatística
Introduction: HIV and AIDS is a global public health problem, responsible for about 32.7 million deaths from AIDS-related diseases from the beginning of the epidemic to the end of 2019, compromising health, workforce and productivity. This scenario tends to be more serious when it comes to military forces, whose responsibility for the defense and maintenance of peace falls on them. The objective was to evaluate the clinical and epidemiological profile and factors associated with viral load non-suppression in patients living with HIV/AIDS at the Military Hospital (CITRA/HMM). Methods: This is a analytic cross-sectional study with a quantitative approach, using secondary data from patients being followed up between the years 2019-2020 at CITRA/HMM. The sample consisted of 9,015 individuals aged 15 years and over. Data analysis was performed with the statistical package STATA, Version 16. Pearson's chi-square test and odds ratio/OR with a confidence interval of 95%CI and p<0,05 were used to verify the differences between the proportions and association between the variables under analysis, considering the state of viral suppression as an outcome: suppressed (<1000 HIV RNA copies/ml) and non-suppressed (≥1000 HIV RNA copies/ml). For the multiple logistic regression model, only the variables that proved to be statistically significant in the bivariate analysis were selected. Results: Of the 9,105 individuals included in the analysis, 4,808 (52.8%) were female and 1,235 (13.6%) were military personnel. The average age was 47.9 years (SD±12.1), with the most prevalent age group being individuals aged between 25 and 59, totalling 7,297 (80.2%) participants. Among those analysed, 5,395 (53.3%) had their last viral load results, and of these, 4,148 (76.9%) had a suppressed viral load. Although the highest proportion of viral suppression was seen in civilians, when adjusted, this difference was not statistically significant
Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Viral Load/immunology , Anti-Retroviral Agents/administration & dosage , Acquired Immunodeficiency Syndrome/prevention & control , HIV/classification , Sustained Virologic Response , MozambiqueABSTRACT
Pope Francis visited Mozambique from September 4-6, 2019. During the visit, a real-time surveillance system for mass gathering events was implemented in all places where people gathered in Maputo City for early detection of possible outbreaks and other health-related events. The system was implemented at four sites were mass gathering events occurred over the three-day visit. Data were collected by administering a simple questionnaire on a tablet, which collected information about sociodemographics, syndromic diagnoses, and outcomes of the patients that sought medical care. Additionally, a descriptive epidemiological assessment was performed during the event. A total of 150 individuals were attended at the designated places during the event. Of these, 56.7% were female and 90.7% aged > 15 years. The majority of the patients (74.7%) sought care on the third day of the event, which was held at the Zimpeto National Stadium. The most common diagnoses were hypertension (20.7%), hypothermia (15.3%), and headache (11.3%). Almost all cases (95.0%) were discharged, (4.0%) cases were transferred and (1.0%) case resulted in death on the way to the health facility. The surveillance system strategy developed to detect real-time public health events during the Pope?s visit was successfully implemented. No outbreak was identified during the event.
Subject(s)
Catholicism , Disease Outbreaks , Patient Acceptance of Health Care/statistics & numerical data , Public Health Surveillance , Public Health , Adolescent , Adult , Aged , Aged, 80 and over , Child , Disease Outbreaks/prevention & control , Female , Humans , Male , Middle Aged , Mozambique , Surveys and Questionnaires , Young AdultABSTRACT
Pope Francis visited Mozambique from September 4-6, 2019. During the visit, a real-time surveillance system for mass gathering events was implemented in all places where people gathered in Maputo City for early detection of possible outbreaks and other health-related events. The system was implemented at four sites were mass gathering events occurred over the three-day visit. Data were collected by administering a simple questionnaire on a tablet, which collected information about sociodemographics, syndromic diagnoses, and outcomes of the patients that sought medical care. Additionally, a descriptive epidemiological assessment was performed during the event. A total of 150 individuals were attended at the designated places during the event. Of these, 56.7% were female and 90.7% aged > 15 years. The majority of the patients (74.7%) sought care on the third day of the event, which was held at the Zimpeto National Stadium. The most common diagnoses were hypertension (20.7%), hypothermia (15.3%), and headache (11.3%). Almost all cases (95.0%) were discharged, (4.0%) cases were transferred and (1.0%) case resulted in death on the way to the health facility. The surveillance system strategy developed to detect real-time public health events during the Popes visit was successfully implemented. No outbreak was identified during the event.
