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Vestn Oftalmol ; 114(6): 10-4, 1998.
Article in Russian | MEDLINE | ID: mdl-9951376

ABSTRACT

Comprehensive (optic, electron, and fluorescent microscopy) morphological analysis of vitreous fragments removed in vitrectomy after penetrating wounds of the eye complicated by hemophthalmia showed that blood and damaged cells of pigment-free ciliary epithelium and the glia play an important role in the development of proliferative processes in the ophthalmic cavity. Immunohistochemical studies revealed active expression of immunoglobulins A and G and of HLA-DR antigen on immunocompetent cells and abnormal expression of HLA-DR in pigment-free ciliary epithelium and the glia, confirming the autoimmune origin of inflammatory disorders.


Subject(s)
Eye Hemorrhage/pathology , Eye Injuries, Penetrating/pathology , Retina/ultrastructure , Vitreoretinopathy, Proliferative/pathology , Vitreous Body/ultrastructure , Ciliary Body/injuries , Ciliary Body/metabolism , Ciliary Body/ultrastructure , Epithelium/immunology , Epithelium/metabolism , Epithelium/ultrastructure , Eye Hemorrhage/complications , Eye Hemorrhage/immunology , Eye Injuries, Penetrating/complications , Eye Injuries, Penetrating/immunology , Fluorescent Antibody Technique , Follow-Up Studies , HLA-DR Antigens/biosynthesis , Humans , Immunoglobulin A/biosynthesis , Immunoglobulin G/biosynthesis , Microscopy, Fluorescence , Retina/injuries , Retina/metabolism , Retinal Ganglion Cells/immunology , Retinal Ganglion Cells/metabolism , Retinal Ganglion Cells/ultrastructure , Rupture , Sclera/injuries , Vitreoretinopathy, Proliferative/etiology , Vitreoretinopathy, Proliferative/immunology , Vitreous Body/injuries , Vitreous Body/metabolism
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