ABSTRACT
Etiopathogenesis and clinical management of TMJD integrates a number of medical disciplines. In particular, dentistry, oral - facial surgery, neurology, rheumatology and so on. Nowadays there is no unified strategy for the management of this disease. Most cases of temporomandibular disorder (TMD) respond to simple treatment and the prognosis is good. Symptoms usually remit with simple care. In cases of secondary involvement of temporomandibular joint (TMJ), the prognosis depends on the primary disease. A comprehensive, chronological history and physical and examination of the patient, including dental history and examination, is essential to diagnose the specific condition to decide further investigations, if any, and to provide specific treatment. in severe cases, a joint consultation of a dentist, neurologist and rheumatologist is needed.
Subject(s)
Temporomandibular Joint Disorders/diagnosis , Temporomandibular Joint Disorders/pathology , Temporomandibular Joint/pathology , Adult , Facial Pain/complications , Facial Pain/diagnosis , Facial Pain/pathology , Humans , Temporomandibular Joint Disorders/complications , Temporomandibular Joint Disorders/etiology , Temporomandibular Joint Disorders/therapyABSTRACT
Drug allergy represents the dominant problem of twenty first century. Number of heavy allergic reactions is increased that is obvious through the increasing number of hospitalizations. Mentioned problem is extended through the rapid development of pharmaceutical industry. Lots of drugs industrialized on a drug market aren't analyzed properly and give rise to undesirable allergic reactions. Diagnostics of drug allergy requests some methodical approaches: detailed collection of Allergic anamnesis and appropriate in vivo and in vitro test sampling. Questionnaire, formulated under the patronage of European Association of Allergologist and clinical Immunologists ensures standard directives for the collection of detailed allergic Anamnesis. Foreseeing the regional peculiarities, we have formulated the simplified version of the questionnaire. In case of positive answer analysis are accompanied and made by Allergologist who makes the sampling of in vivo and in vitro tests.
Subject(s)
Drug Hypersensitivity/diagnosis , Drug Hypersensitivity/etiology , Surveys and Questionnaires , Anaphylaxis/chemically induced , Drug Hypersensitivity/prevention & control , Drug-Related Side Effects and Adverse Reactions , Humans , Intradermal TestsABSTRACT
Severe oxidative stress, developed under experimental periodontitis is accompanied by disturbances in mitochondrial respiration in tissue cells of gingiva, membrane damage and release of Fe(2+) and Mn(2+), leading to the worsening of inflammation process and gingival tissue necrosis. Reduction of free nitric oxide in gingival tissue appeared to be characteristic for experimental parodontitis: decreases local immunity, antimicrobial resistance, and tissue regeneration, disturbs blood supply and tissue trophism, which forwards important role in deepening of inflammation process and wasting of gingival tissue. Application of preparations derived from black poplar (Populus Nigra) gemma standardizes mitochondrial respiration, reduces presentation of inflammation, and considerably improves EPR-spectrum of gingival tissue. Though the complete normalization is not achieved--hazard of peroxidation still remains, the applied preparations, due to their strong anti- oxidative and anti-inflammatory activities is as an effective and rehabilitative means to tackle gingivitis and peiodontitis.
Subject(s)
Periodontitis/drug therapy , Plant Preparations/administration & dosage , Populus , Administration, Topical , Animals , Disease Models, Animal , Ointments , Rats , Treatment OutcomeABSTRACT
Studied were 37 patients in which defects and deformations of various etiology were corrected using plastic with local tissues excised from face and neck. Polarography, thermography and thermometry proved that 5 sessions of hyperbaric oxygenation (HO) at 1.5 atm. sharply reduced the incidence of complications after the surgery. This effect was accounted for by providing optimal conditions to accelerate the microcirculatory improvement, oxygen transport and tissue utilization. HO decreased the incidence of complications that influence the reconstructive surgery outcome.