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1.
J Arthroplasty ; 27(8): 1581.e9-1581.e11, 2012 Sep.
Article in English | MEDLINE | ID: mdl-22425294

ABSTRACT

We present a case of a pseudotumor causing a deep femoral vein thrombosis 16 months after undergoing a metal-on-metal total hip arthroplasty. There is increasing concern over the effect of metal ions that are produced by wear in metal-on-metal hip arthroplasty systems. Recently, a number of articles have reported the development of an inflammatory pseudotumor causing a number of different problems early on in the lifespan of the implant necessitating revision surgery. This case reports the first presentation of a pseudotumor causing a serious venous thrombosis due to pressure effect and indicates further possible evidence for caution when considering metal-on-metal bearing hip arthroplasty.


Subject(s)
Femoral Vein , Granuloma, Plasma Cell/complications , Granuloma, Plasma Cell/etiology , Hip Prosthesis/adverse effects , Metal-on-Metal Joint Prostheses/adverse effects , Thrombosis/etiology , Humans , Male , Middle Aged , Prosthesis Design
2.
BJU Int ; 105(3): 390-4, 2010 Feb.
Article in English | MEDLINE | ID: mdl-19709070

ABSTRACT

STUDY TYPE: Therapy (case series). LEVEL OF EVIDENCE: 4. OBJECTIVE: To present our institution's experience of selective embolization of renal angiomyolipomas with alcohol and the long-term follow up data. PATIENTS AND METHODS: This retrospective study included 34 patients treated between October 1997 and October 2007 (29 women and five men, mean age 44 years). Of these patients, nine had tuberous sclerosis, 14 were bilateral and 16 were multifocal. Indications for treatment were previous haemorrhage (14), size >4 cm (19) and increasing size over a short period (one). The largest treated lesion was 24.4 cm, and the mean (range) size was 11.9 (2.9-24.4) cm. All patients were treated by selective embolization using a mixture of alcohol and lipiodol. Three patients also had coiling of aneurysms and two patients had additional embolization with polyvinyl alcohol particles. The follow-up was both radiological and clinical, with recurrence defined as growth by >2 cm or symptoms requiring further treatment. RESULTS: The technical success rate was 100%, with only one significant complication of non-target renal embolization, with self-limiting effects. Minor complications included 11 patients with post-embolization syndrome, all of which settled with conservative measures. The mean (range) combined radiological and clinical follow-up was 44.2 (12-116) months, with all patients having a follow-up of >1 year. Radiological success was achieved in 97%, with only one lesion growing by >2 cm. The combined clinical and radiological success rate was 85%, with two patients undergoing surgery, two having repeat embolization and one currently offered surgery due to a recent increase in size. CONCLUSION: Our study provides long-term evidence that selective arterial embolization with alcohol is a safe and effective method for improving clinical symptoms (85%) and preventing tumour progression (97%) in patients with renal angiomyolipoma.


Subject(s)
Angiomyolipoma/therapy , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Chemoembolization, Therapeutic/methods , Ethanol/administration & dosage , Iodized Oil/administration & dosage , Kidney Neoplasms/therapy , Adult , Aged , Angiomyolipoma/diagnostic imaging , Disease Progression , Female , Humans , Kidney Neoplasms/diagnostic imaging , Male , Middle Aged , Neoplasm Recurrence, Local/etiology , Radiography, Interventional , Retrospective Studies , Treatment Outcome , Young Adult
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