ABSTRACT
The purpose of this article is to review impression materials used for fabricating fixed restorations in dentistry. Their compositions, properties, advantages, and disadvantages are presented and compared. How these properties influence clinical decisions is also described. This review helps the clinician choose which material is more suitable for a specific case. A broad search of the published literature was performed using Medline to identify pertinent current articles. Textbooks, the Internet, and manufacturers' literature were also used to supplement this information. It is limited to impression materials used in fixed prosthodontics. The review gives basic knowledge of ideal impression material properties and discusses traditional and, primarily, more recently developed products, such as polyethers, poly(vinyl siloxane), polysulfides, and condensation silicone materials. Clear advantages and disadvantages for these impression materials are provided along with the role that compositional variations have on the outcome of the impression. This should enable clinicians and technicians to easily identify the important physical properties of each type of impression material and their primary clinical indications.
Subject(s)
Dental Impression Materials , Denture, Partial, Fixed , Dental Impression Materials/chemistry , Dental Impression Materials/classification , Dental Impression Materials/standards , Drug Incompatibility , Elasticity , Ethers , Humans , Hydrophobic and Hydrophilic Interactions , Models, Dental , Polyvinyls , Reproducibility of Results , Rheology , Silicones , Siloxanes , Sulfides , ViscosityABSTRACT
The exchange of fluids and chemicals between the tooth pulp and the periphery, through the dentinal tubules has been well documented. Application of irritants on the open tubules produces aversion in awake rats that can be prevented by prior occlusion of these tubules. This study aims at characterizing the secretion of inflammatory mediators in tooth perfusates and assessing the effects of systemic pretreatment with anti-inflammatory drugs on the levels of these mediators. Several groups of rats (n=5-6 each) were used for intradental application of either saline, capsaicin (100 microg in 100 microl), or endotoxin (20 microg in 100 microl) for a period of 40 min followed by filling the perfusion chamber with sterile saline and collecting the perfusate every 30 min for 6h. The perfusates were used for the determination of the concentrations of cytokines by ELISA. Application of irritants produced a highly significant increase in PGE2 (peak at 2h) and NGF (peak at 4-6h). Dexamethasone antagonized the effects of endotoxin and capsaicin, while NSAID affected mainly the endotoxin-induced inflammation. Our results confirm the validity of the tooth perfusion technique and demonstrate that the efficacy of treatment with anti-inflammatory drugs depends on the type of inflammation.
Subject(s)
Anti-Inflammatory Agents/pharmacology , Incisor , Inflammation Mediators/metabolism , Irritants/pharmacology , Analgesics, Opioid/pharmacology , Animals , Anti-Inflammatory Agents/immunology , Capsaicin/pharmacology , Celecoxib , Dexamethasone/pharmacology , Dinoprostone/metabolism , Endotoxins/pharmacology , Incisor/drug effects , Incisor/injuries , Indomethacin/pharmacology , Morphine/pharmacology , Nerve Growth Factor/metabolism , Pyrazoles/pharmacology , Rats , Rats, Sprague-Dawley , Sensory System Agents/pharmacology , Sulfonamides/pharmacologyABSTRACT
OBJECTIVES: Application of irritants on the exposed dentine of the incisors has been shown to produce aversive behaviour in awake rats. This study aims to demonstrate that the observed aversion is due to the infiltration of irritants through the dentinal tubules and the activation of capsaicin sensitive fibres in the tooth pulp. METHODS: Different groups of rats were subjected, under anaesthesia, to cutting of the distal 2 mm of their lower incisors and the fixation of an artificial crown that allows the application of 10-15 microl of solution. Several procedures were followed to prevent the action of the irritants including occlusion of the dentinal tubules, local application of lidocaine, selective ablation of the capsaicin sensitive primary afferents (CSPA) or incisor pulpectomy; the reactions to intradental application of either capsaicin (1%) or formalin (2.5%) were tested using a newly designed behavioural score. RESULTS: Occlusion of dentinal tubules produced significant attenuation of the nociceptive behaviour induced by dentinal application of either capsaicin or formalin. Similar results were observed following either local block with lidocaine (2%), selective ablation of capsaicin sensitive afferents or total denervation by pulpectomy. CONCLUSIONS: The present results confirm the hypothesis of infiltration of irritants to the incisor pulp through the dentinal tubules and suggest that the reported inflammatory reaction and hyperalgesia are mediated, to a large extent, by capsaicin sensitive primary afferents.
