ABSTRACT
The first case of intraocular sparganosis presenting as endophthalmitis is reported with a live plerocercoid larva of Spirometra lodged in the anterior chamber of the eye of a man in India. The larva was identified histologically.
Subject(s)
Endophthalmitis/pathology , Eye Infections, Parasitic/pathology , Sparganosis/pathology , Adult , Animals , Humans , India , Larva , Male , SparganumABSTRACT
Serum beta-2 microglobulin levels were measured in 68 patients with acute idiopathic anterior uveitis and 51 healthy subjects by ELISA technique. The levels were found to be significantly increased in moderate and severe types of uveitis despite a normal renal glomerular function in all patients. The parameters remained unaltered in mild types. Serum beta-2 microglobulin levels closely paralleled the severity of the disease. The increased beta-2 microglobulin level in serum showed a significant fall to normal levels on clinical improvement. The data further strengthen the hypothesis that acute idiopathic anterior uveitis is an immune mediated disease. It is proposed that serum beta-2 microglobulin may be considered as a reliable parameter of the degree of severity of acute idiopathic anterior uveitis, as well as representing a useful tool for the evaluation of drug efficacy, especially in intractable cases.
