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2.
J Am Acad Orthop Surg ; 18(7): 426-35, 2010 Jul.
Article in English | MEDLINE | ID: mdl-20595135

ABSTRACT

Persons with diabetes undergo more surgical procedures, have a higher perioperative risk of complications, and have longer hospital stays than do persons who do not have diabetes. Persons with diabetes are frequently overweight, have a high prevalence of cardiovascular risk factors, and are more likely to suffer from chronic musculoskeletal conditions and traumatic injuries that require orthopaedic attention. Surgery frequently disrupts usual diabetes management, requiring adjustments to the treatment regimen. Suboptimal perioperative glucose control may contribute to increased morbidity, and it aggravates concomitant illnesses. Many patients undergoing elective or urgent orthopaedic surgery may have unrecognized diabetes or may develop stress-related hyperglycemia in the hospital. The challenge is to minimize the effects of metabolic derangements on surgical outcomes, reduce glycemic excursions, and prevent hypoglycemia. Recent guidelines advocate evidence-based glucose targets in the inpatient setting, and regimens for intravenous and subcutaneous insulin are gaining in popularity. Individualized treatment should be based on the ambient level of glycemic control, outpatient treatment regimen, presence of complications, nature of the surgical procedure, and type of anesthesia administered. Management by a multidisciplinary team and attention to discharge planning are key aspects of care during and after orthopaedic surgery.


Subject(s)
Diabetes Mellitus/epidemiology , Diabetes Mellitus/therapy , Hyperglycemia/therapy , Orthopedic Procedures , Comorbidity , Critical Care , Diabetes Mellitus, Type 1/therapy , Diabetes Mellitus, Type 2/epidemiology , Diabetes Mellitus, Type 2/therapy , Diabetic Angiopathies/surgery , Diabetic Ketoacidosis/prevention & control , Drug Therapy, Combination , Hyperglycemia/epidemiology , Hypoglycemia/prevention & control , Hypoglycemic Agents/administration & dosage , Hypoglycemic Agents/pharmacology , Insulin/administration & dosage , Length of Stay , Perioperative Care
3.
J Invest Surg ; 22(5): 368-74, 2009.
Article in English | MEDLINE | ID: mdl-19842892

ABSTRACT

We prospectively examined the relationship between pre- and postoperative range of motion utilizing three cruciate retaining knees with various mechanical flexion potentials, i.e., two at about 130 degrees -135 degrees (one with posterior lip and the other without) and the third at about 140 degrees -145 degrees . All groups demonstrated mean flexion and range of motion of 116 degrees -122 degrees at one year. Combining data from the three cohorts, patients with the following preoperative flexion values achieved the indicated mean changes (increases) in flexion at one year: < 90 degrees flexion (Delta 23.6 degrees ), 91 degrees -105 degrees flexion (Delta 19.3 degrees ), and > 105 degrees flexion (Delta 1.8 degrees )). Postoperative improvement was inversely related to preoperative flexion. The high flex knee yielded the best improvement in range of motion (9.7 degrees increase) in the highest flex preoperative group compared to that of the other knees (-7.4 degrees to 2.9 degrees ). Hence, a high flex knee design seems to be important in high preoperative range of motion patients obtaining an increase in the postoperative range of motion rather than possible regression.


Subject(s)
Arthroplasty, Replacement, Knee/methods , Knee Joint/surgery , Knee Prosthesis , Range of Motion, Articular , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Prospective Studies , Treatment Outcome
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